(Division of Cancer Treatment and Diagnosis) sponsored studies with monitoring done via CTMS (Clinical Trials Monitoring Service), electronically report data to


every two weeks according to the following calendar:
Theradex Reference Documents


C3D uses the

CCR eCRF Instructions Manual 2011

and submitted data is sent according to the CTMS specification.





(Cancer Therapy Evaluation Program) sponsored studies utilizing


(Clinical Data Update System), electronically report data every quarter (January, April, July and October).


CTEP Reference Documents


For studies that do not submit data via CDUS, data must be submitted (manually) via the

CDS Application

This is also known as the CDUS Web Submission.


Pharmaceutical Sponsors

For PI initiated studies where industry is the sponsor, please remember that C3D might be able to be used and data transferred to the sponsor via a secured file transfer process. Ideally, this discussion needs to begin early in the collaborative process and the CTA, or other tech transfer agreement should include the data to be transferred and the time frame for transfer. The document below are the specifications that you can send to the sponsor to begin the dialogue on using C3D and how data transfer can occur:


C3D Electronic Data Submission Capabilities


Last updated by Paul, Rohit (NIH/NCI) [E] on Nov 19, 2017