• Restricted Page
  • Login Required

CCR Science Board

Skip to end of metadata
Go to start of metadata

CCR Technology Development Award


New technology is a major driver of discovery. Development of new methods and technology is challenging within an individual PI’s laboratory as it often requires interdisciplinary expertise and a team of collaborating researchers. In other cases, ideas for new methods often arise from cursory observations in the lab and their further pursuit may fall outside the immediate focus of a PI’s research program. Methods development is almost invariably a high-risk enterprise.

The CCR is seeking proposals for the development of ground-breaking new methods and technology in any area of biomedicine ranging from basic research tools to clinical technology. Proposals should build strongly on observations made in the PI’s laboratory.


High-priority goals for proposed projects include, but are not limited to:

  • Development of transformational new technologies for application in any area of basic research
  • Development of high-impact diagnostic or prognostic methods
  • Development of ground-breaking clinical technology

Selection Criteria

Key criteria for evaluation of proposals are:

  • Potential impact of methodology: Successful projects will develop methods that have the potential to be used by a wide community of basic and/or clinical researchers. Methods that are primarily useful to the submitting PIs are not suitable.
  • Degree of innovation: The method to be developed must be novel. Improvements of existing methods or application of existing technology to new experimental systems or clinical settings are not suitable.
  • Feasibility:  The PI must provide evidence for the feasibility of the proposed method and demonstrate relevant expertise. Preliminary data to demonstrate feasibility is encouraged, but not required.
  • Milestones: The proposal should list clearly defined milestones and identify at least annual go/no-go decision points.


Applicants must be a CCR intramural Tenure-track PI, Tenured PI, Senior clinician or Senior scientist in the Center for Cancer Research.  Those in the Physician-Scientist Early Investigator (PEI) program can apply but must include a tenured PI as a co-PI. Staff Scientists with independent budgets (CANs) are eligible. Non-NCI researchers can act as collaborators but can not receive funds. Please click here for more specifics on who may apply.


Funding will be provided for up to 3 years and up to $125,000 per year to cover personnel and supply costs. A detailed budget is required to justify requested funds.

Review Process

Review of proposals will occur in two stages. After initial review of Letters of Intent (LOI), shortlisted proposals (approximately 20% of LOIs) will be invited for full review.

LOI and invited proposals will be evaluated by the CCR Science Board.

Application process and format

LOI and invited proposals are to be submitted to ProposalCentral.

Click for instructions on preparing an application.

Important Deadlines

Invited Proposals are due on December 2, 2020

Last updated by Linnekin, Diana (NIH/NCI) [E] on Oct 19, 2020