Before you can use your account for the first time, you must change the password provided to you.
After changing the password for the first time, wait for an hour before attempting to log into iRIS.
Use the NIH iForgotMyPassword to change your Password and maintain your Security Questions.
Select NIHEXT Domain, enter your Account's Use Name and click on the Agree button.
Note that the Password can only be changed once in a 24 hour period.