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The Center for Cancer Research announces a course for researchers using animal models: Mouse Research Models (MRM) or Mouse 101

Go to Registration Page

Click here to Register for Mouse 101

Mouse research models play an important role in cancer research. Technologies available today allow researchers to create mouse models of cancer by transferring new genes into animals or inactivating existing genes. Mouse research models can be used to study the changes associated with tumor development, test new approaches to detection and diagnosis and to evaluate prevention and treatment strategies. MRM/Mouse 101 will provide an overview of the procedures used at NIH to conduct research using mice and explore how mouse research models can be used in cancer research. The course is designed for fellows, technicians, and investigators who plan to conduct experiments using mouse research models at NIH.

Location and Time:
The MRM course will be held on May 7, 15, 22 and 29 from 9:00 a.m. – 1:00 p.m. in Building 45, Natcher Conference Center, Balcony A/B* with video-conference to Frederick National Laboratory for Cancer Research (FNL), Building 549 Auditorium.

* Balcony A on 5/15; Balcony B on 5/7, 5/22, and 5/29

Several hands-on training modules in various common mouse techniques will be offered to small groups on additional dates to be announced at the course.

Archived Presentations:
The presentations included in this course will be recorded and archived on the CCR Lectures website:

Your NIH username and password are required to access this course.

Register by clicking on the link at the top of the page. The deadline for registration is April 30, 2012. For more information contact Romi Sawhney by email at (mailto: ?or by phone (301-451-2277). There is no fee for this course but seating is limited. Registration is on first come first serve basis. Certificates of completion will be provided to registrants who attend the course.

Course Syllabus:

May 7, 2012, 9:00 a.m. to 1:00 p.m. - Bldg. 45 Balcony B




Preparation of the NCI Animal Study Proposal

T. Sadr/A. Stahl

Overview of core animal services

L. Feigenbaum

Effective Colony Management

The Jackson Laboratory

Survival Surgery


     • Bone marrow transplant

X. Tai

     • Skin Grafts

C. Cataisson

     • Partial hepatectomy

V. Factor

May 15, 2012, 9:00 a.m. to 1:00 p.m. - Bldg. 45 Balcony A


In Vivo Imaging


     • In vivo Optical Imaging

P. Choyke

     • Intravital Imaging

S. Lockett/Amiran Dzutsev

     • Image Analysis

J. Kalen

Drug Studies in Mouse Models

     • Human to Mouse

M. Hollingshead

     • Mouse to Mouse

S. Difilippantonio

Drug Studies in Other Animal Models

M. Paoloni


S. Manna

May 22, 2012, 9:00 a.m. to 1:00 p.m. - Bldg. 45 Balcony B


Histology/Histopathology and related techniques

M. Simpson


B. Hoyt

Practical Aspects of the Mouse Immune System

H. Park

     • Flow cytometry

S. Sharrow


M. Rao

Common Techniques used in Cancer Models - Module 1


May 29, 2012, 9:00 a.m. to 1:00 p.m. - Bldg. 45 Balcony B


Mouse Genetics

D. Watkins-Chow

Construct Design for Mouse Models      


     • Complex and Inducible


     • Recombineering

N. Pruett

     • Gateway Technology

D. Esposito

     • Adenovirus/Lentivirus

R. Bagni

Common Techniques used in Cancer Models - Module 2


  • None