Welcome to the DNA Topoisomerase/Integrase Group's Wiki Home page.
This web site provides additional information on the research performed by the DNA Topoisomerase/Integrase Group, LMP, which focuses on Topoisomerase, HIV-1 integrase and Tdp1 inhibitors. Our group is part of the Laboratory of Molecular Pharmacology, CCR.
HIV-1 Integrase Mutations Table
To view a comprehensive list of all the HIV-1 integrase reported mutations and their impact on catalytic activity and clinical resistance to integrase inhibitors, click here.
This web site is maintained by Dr. Christophe Marchand.