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Welcome to the DNA Topoisomerase/Integrase Group's Wiki Home page.

This web site provides additional information on the research performed by the DNA Topoisomerase/Integrase Group, LMP, which focuses on Topoisomerase, HIV-1 integrase and Tdp1 inhibitors. Our group is part of the Laboratory of Molecular Pharmacology, CCR.

HIV-1 Integrase Mutations Table

To view a comprehensive list of all the HIV-1 integrase reported mutations and their impact on catalytic activity and clinical resistance to integrase inhibitors, click here.

This web site is maintained by Dr. Christophe Marchand.

Last updated by Marchand, Christophe (NIH/NCI) [E] on Mar 24, 2010