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Center of Excellence in Chromosome Biology

Chromosome biology in the 21st century focuses on genome function in the context of the intact eukaryotic cell nucleus. Its goals are a comprehensive understanding of the mechanisms involved in chromosome function, and the correction of aberrations in these processes that lead to disease.

The Center of Excellence in Chromosome Biology (CECB), open to all NCI intramural investigators, brings together experts from fields such as dynamics of chromatin structure and function; epigenetics and gene expression; chromosome segregation and cell division; DNA replication, repair, and recombination; chromosome organization and gene localization; and nuclear protein interaction dynamics. The CECB integrates the intellectual and physical resources within NCI's Intramural Research Program to support outstanding research in chromosome biology. 

Objectives

• Promote interaction and collaboration among researchers within the NCI, NIH, and beyond

• Promote advances and opportunities for research in chromosome biology

• Leverage cutting-edge tools, approaches, and resources to advance chromosome biology as it applies to cancer research

• Train young investigators to address complex scientific questions through collaboration and multi-disciplinary approaches