Access Keys:
Skip to content (Access Key - 0)

Center For Cancer Research National Cancer Institute
JB6 Mouse Model

  1. Kim JE, Son JE, Jang YJ, Lee DE, Kang NJ, Jung SK, Heo YS, Lee KW, Lee HJ.  Luteolin, a novel natural inhibitor of TPL2 kinase, inhibits tumor necrosis factor-alpha-induced cyclooxygenase-2 expression in JB6 mouse epidermis cells.  Pharmacol Exp Ther. [Epub ahead of print, 2011.]  Abstract 
  2. Wittwer JA, Robbins D, Wang F, Codarin S, Shen X, Kevil C, Huang TT, Remmen H, Richardson A, Zhao Y.  Enhancing Mitochondrial Respiration Suppresses Tumor Promoter TPA Induced PKM2 Expression and Cell Transformation in Skin Epidermal JB6 Cells.  Cancer Prev Res (Phila).  [Epub ahead of print], 2011.  Abstract 
  3. Lau AT, Lee SY, Xu YM, Zheng D, Cho YY, Zhu F, Kim HG, Li SQ, Zhang Z, Bode AM, Dong Z.  Phosphorylation of histone H2B serine 32 is linked to cell transformation.  J Biol Chem.  [Epub ahead of print], 2011.  Abstract 
  4. Han CY, Hien TT, Lim SC, Kang KW.  Role of Pin1 in UVA-induced cell proliferation and malignant transformation in epidermal cells.  Biochem Biophys Res Commun.  410(1):68-7, 2011.  Abstract 
  5. Lim TG, Kwon JY, Kim J, Song NR, Lee KM, Heo YS, Lee HJ, Lee KW.    Cyanidin-3-glucoside suppresses B[a]PDE-induced cyclooxygenase-2 expression by directly inhibiting Fyn kinase activity.  Biochem Pharmacol. 82(2):167-74, 2011.  Abstract 
  6. Mukherjee JJ, Kumar S, Gocinski R, Williams J.  Phenolic fraction of tobacco smoke inhibits BPDE-induced apoptosis response and potentiates cell transformation: role of attenuation of p53 response.  Chem Res Toxicol.  24(5):698-705. doi: 10.1021/tx100440, 2011.  Abstract 
  7. Lee SJ, Nam KW, Mar W.  Effects of psoralen from Psoralea corylifolia on quinone reductase, ornithine decarboxylase, and JB6 cells transformation promotion.  Arch Pharm Res. 34(1):31-6, 2011.  Abstract 
  8. Park EJ, Kondratyuk TP, Morrell A, Kiselev E, Conda-Sheridan M, Cushman M, Ahn S, Choi Y, White JJ, van Breemen RB, Pezzuto JM.  Induction of retinoid X receptor activity and consequent upregulation of p21WAF1/CIP1 by indenoisoquinolines in MCF7 cells.  Cancer Prev Res (Phila).  4(4):592-60, 2011.  Abstract 
  9. Khanal P, Choi HK, Namgoong GM, Ahn SG, Yoon JH, Sohn H, Choi HS.  5'-Nitro-indirubinoxime inhibits epidermal growth factor- and phorbol ester-induced AP-1 activity and cell transformation through inhibition of phosphorylation of Pin1.  Mol Carcinog.  10.1002/mc.2076, 2011.  Abstract 
  10. Lee DE, Lee KW, Byun S, Jung SK, Song N, Lim SH, Heo YS, Kim JE, Kang NJ, Kim BY, Bowden GT, Bode AM, Lee HJ, Dong Z.   7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4.  J Biol Chem.  286(16):14246-56, 2011.  Abstract 
  11. Shin JW, Ohnishi K, Murakami A, Lee JS, Kundu JK, Na HK, Ohigashi H, Surh YJ.  Zerumbone Induces Heme Oxygenase-1 Expression in Mouse Skin and Cultured Murine Epidermal Cells through Activation of Nrf2.  Cancer Prev Res (Phila).  4(6):860-70, 2011.  Abstract 
  12. Kim JE, Lee DE, Lee KW, Son JE, Seo SK, Li J, Jung SK, Heo YS, Mottamal M, Bode AM, Dong Z, Lee HJ.  Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K.  Cancer Prev Res (Phila).  4(4):582-91, 2011.  Abstract 
  13. Kang NJ, Lee KW, Kim BH, Bode AM, Lee HJ, Heo YS, Boardman L, Limburg P, Lee HJ, Dong Z.  Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK.   Carcinogenesis.  32(6):921-8, 2011.  Abstract 
  14. Zhang Y, Wang Q, Guo X, Miller R, Guo Y, Yang HS.  Activation and up-regulation of translation initiation factor 4B contribute to arsenic-induced transformation.  Mol Carcinog.  50(7):528-38. doi: 10.1002/mc.20733, 2011.  Abstract 
  15. Khanal P, Oh WK, Yun HJ, Namgoong GM, Ahn SG, Kwon SM, Choi HK, Choi HS.  p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis.  Carcinogenesis 32(4):545-53, 2011.  Abstract 
  16. Li T, Zhang J, Zhu F, Wen W, Zykova T, Li X, Liu K, Peng C, Ma W, Shi G, Dong Z, Bode AM, Dong Z.  P21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformation.  Carcinogenesis 32(5):659-66, 2011.  Abstract 
  17. Yoon JH, Lim TG, Lee KM, Jeon AJ, Kim SY, Lee KW.  Tangeretin reduces ultraviolet B (UVB)-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking mitogen-activated protein kinase (MAPK) activation and reactive oxygen species (ROS) generation.  J Agric Food Chem.  59(1):222-8, 2011.  Abstract 
  18. Liu K, Cho YY, Yao K, Nadas J, Kim DJ, Cho EJ, Lee MH, Pugliese A, Zhang J, Bode AM, Dong Z, Dong Z.  Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation.  J Biol Chem. 2011 Jan 21;286(3):2057-66, 2011.  Abstract