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Center For Cancer Research National Cancer Institute
JB6 Mouse Model

JB6 References 2007
  1. Nomura M, Yamazaki R, Takaya M, Kikuchi M, Takahashi-Nishioka T, Akiyama K, Akiyama N, Moritani S, & Kobayashi S. Inhibition of tetrandrine on epidermal growth factor-induced cell transformation and its signal transduction. Anticancer Res 27(5A): 3187-93, 2007.  Abstract 
  2. Lee KM, Kang NJ, Han JH, Lee KW, & Lee HJ. Myricetin down-regulates Phorbol ester-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking activation of nuclear factor kappa B. J Agric Food Chem 55(23): 9678-84, 2007.  Abstract 
  3. Huang X, Dai J, Huang C, Zhang Q, Bhanot O, & Pelle E. Deferoxamine synergistically enhances iron-mediated AP-1 activation. A showcase of the interplay between extracellular-signal-regulated kinase and tyrosine phosphatase. Free Radic Res 41(10): 1135-42, 2007.  Abstract 
  4. Cho YY, Yao K, Kim HG, Kang BS, Zheng D, Bode AM, & Dong Z. Ribosomal S6 kinase 2 is a key regulator in tumor promoter induced cell transformation. Cancer Res 67(17): 8104-12, 2007.  Abstract  Full Text
  5. Kang NJ, Lee KW, Rogozin EA, Cho YY, Heo YS, Bode AM, Lee HJ, & Dong Z. Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway. J Biol Chem 282(45): 32856-66, 2007.  Abstract 
  6. Ma C, Wang J, Gao Y, Gao TW, Chen G, Bower KA, Odetallah M, Ding M, Ke Z, & Luo J. The role of glycogen synthase kinase 3beta in the transformation of epidermal cells. Cancer Res 67(16): 7756-64, 2007.  Abstract
  7. Lee KW, Kang NJ, Rogozin EA, Kim HG, Cho YY, Bode AM, Lee HJ, Surh YJ, Bowden GT, & Dong Z. Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1. Carcinogenesis 28(9): 1918-27, 2007.  Abstract
  8. Dhar SK, Xu Y, Noel T, & St Clair DK. Chronic exposure to 12-O-tetradecanoylphorbol-13-acetate represses sod2 induction in vivo. The negative role of p50. Carcinogenesis 28(12): 2605-13, 2007.  Abstract  Full Text
  9. Zhu F, Zykova TA, Kang BS, Wang Z, Ebeling MC, Abe Y, Ma WY, Bode AM, & Dong Z. Bidirectional signals transduced by TOPK-ERK interaction increase tumorigenesis of HCT116 colorectal cancer cells. Gastroenterology 133(1): 219-31, 2007.  Abstract 
  10. Fedorov SN, Shubina LK, Bode AM, Stonik VA, & Dong Z. Dactylone inhibits epidermal growth factor-induced transformation and phenotype expression of human cancer cells and induces G1-S arrest and apoptosis. Cancer Res 67(12): 5914-20, 2007.  Abstract
  11. Yang S, Misner BJ, Chiu RJ, & Meyskens FL Jr. Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells. Carcinogenesis 28(11): 2382-90, 2007.  Abstract
  12. Smetanina OF, Kalinovsky AI, Khudyakova YV, Pivkin MV, Dmitrenok PS, Fedorov SN, Ji H, Kwak JY, & Kuznetsova TA. Indole alkaloids produced by a marine fungus isolate of Penicillium janthinellum Biourge. J Nat Prod 70(6): 906-9. Erratum in. J Nat Prod 70(12): 2054, 2007.  Abstract 
  13. Oh SM, Zhu F, Cho YY, Lee KW, Kang BS, Kim HG, Zykova T, Bode AM, & Dong Z. T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation. Cancer Res 67(11): 5186-94, 2007.  Abstract 
  14. Kao ES, Wang CJ, Lin WL, Chu CY, & Tseng TH. Effects of polyphenols derived from fruit of Crataegus pinnatifida on cell transformation, dermal edema and skin tumor formation by phorbol ester application. Food Chem Toxicol 45(10): 1795-804, 2007.  Abstract 
  15. Ouyang W, Zhang D, Ma Q, Li J, & Huang C. Cyclooxygenase-2 induction by arsenite through the IKKbeta/NFkappaB pathway exerts an antiapoptotic effect in mouse epidermal Cl41 cells. Environ Health Perspect 115(4): 513-8, 2007.  Abstract Full Text
  16. Gu Q, Tan M, & Sun Y. SAG/ROC2/Rbx2 is a novel activator protein-1 target that promotes c-Jun degradation and inhibits 12-O-tetradecanoylphorbol-13-acetate-induced neoplastic transformation. Cancer Res 67(8): 3616-25, 2007.  Abstract 
  17. Zykova TA, Zhu F, Zhang Y, Bode AM, & Dong Z. Involvement of ERKs, RSK2 and PKR in UVA-induced signal transduction toward phosphorylation of eIF2alpha (Ser(51)). Carcinogenesis 28(7): 1543-51, 2007.   Abstract 
  18. Kwon JY, Lee KW, Hur HJ, & Lee HJ. Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2. Ann NY Acad Sci 1095: 513-20, 2007.  Abstract 
  19. Wang SY, Feng R, Bowman L, & Lu Y, Ballington JR, Ding M. Antioxidant activity of Vaccinium stamineum. Exhibition of anticancer capability in human lung and leukemia cells. Planta Med 73(5): 451-60, 2007.  Abstract 
  20. Murray AR, Kisin ER, Kommineni C, Vallyathan V, Castranova V, & Shvedova AA. Pro/antioxidant status and AP-1 transcription factor in murine skin following topical exposure to cumene hydroperoxide. Carcinogenesis 28(7): 1582-8, 2007.  Abstract 
  21. Ichimatsu D, Nomura M, Nakamura S, Moritani S, Yokogawa K, Kobayashi S, Nishioka T, & Miyamoto K. Structure-activity relationship of flavonoids for inhibition of epidermal growth factor-induced transformation of JB6 Cl 41 cells. Mol Carcinog 46(6): 436-45, 2007.  Abstract