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Center For Cancer Research National Cancer Institute
JB6 Mouse Model

JB6 References 2004
  1. Lin MH, Wang CJ, Huang HP, Chou MY, & Chou FP. The tumorigenic haracteristics of lime-piper betel quid-transformed JB6 cells. Arch Toxicol. 78(3): 167-73, 2004.  Abstract 
  2. Hou DX, Kai K, Li JJ, Lin S, Terahara N, Wakamatsu M, Fujii M, Young MR, & Colburn N. Anthocyanidins inhibit activator protein 1 activity and cell transformation. Structure-activity relationship and molecular mechanisms. Carcinogenesis 25(1): 29-36, 2004.  Abstract  
  3. Wong BC, Jiang XH, Lin MC, Tu SP, Cui JT, Jiang SH, Wong WM, Yuen MF, Lam SK, & Kung HF. Cyclooxygenase-2 inhibitor (SC-236) suppresses activator protein-1 through c-Jun NH2-terminal kinase. Gastroenterology 126(1): 136-47, 2004.  Abstract 
  4. Samuel S & Bernstein LR. Adhesion, migration, transcriptional, interferon-inducible, & other signaling molecules newly implicated in cancer susceptibility and resistance of JB6 cells by cDNA microarray analyses. Mol Carcinog 39(1): 34-60, 2004.  Abstract 
  5. Ding M, Lu Y, Bowman L, Huang C, Leonard S, Wang L, Vallyathan V, Castranova V, & Shi X. Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract. J Biol Chem 279(11): 10670-6, 2004.  Abstract 
  6. Wei SJ, Trempus CS, Ali RC, Hansen LA, & Tennant RW: 12-O-tetradecanoylphorbol-13-acetate and UV radiation-induced nucleoside diphosphate protein kinase B mediates neoplastic transformation of epidermal cells. J Biol Chem 279(7): 5993-6004, 2004.  Abstract 
  7. Fedorov SN, Bode AM, Stonik VA, Gorshkova IA, Schmid PC, Radchenko OS, Berdyshev EV, & Dong Z. Marine alkaloid polycarpine and its synthetic derivative dimethylpolycarpine induce apoptosis in JB6 cells through p53- and caspase 3-dependent pathways. Pharm Res 21(12): 2307-19, 2004.  Abstract 
  8. Feng R, Bowman LL, Lu Y, Leonard SS, Shi X, Jiang BH, Castranova V, Vallyathan V, & Ding M. Blackberry extracts inhibit activating protein 1 activation and cell transformation by perturbing the mitogenic signaling pathway. Nutr Cancer 50(1): 80-9, 2004.  Abstract 
  9. Rabah IO, Hou DX, Komine S, & Fujii M. Potential chemopreventive properties of extract from baked sweet potato (Ipomoea batatas Lam. Cv. Koganesengan). J Agric Food Chem 52(23): 7152-7, 2004.  Abstract 
  10. Dai J, Huang C, Wu J, Yang C, Frenkel K, & Huang X. Iron-induced interleukin-6 gene expression. Possible mediation through the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways. Toxicology 203(1-3): 199-209, 2004.  Abstract 
  11. Krysko O, De Ridder L, & Cornelissen M. Phosphatidylserine exposure during early primary necrosis (oncosis) in JB6 cells as evidenced by immunogold labeling technique. Apoptosis 9(4): 495-500, 2004.  Abstract
  12. Zhu F, Zhang Y, Bode AM, & Dong Z. Involvement of ERKs and mitogen- and stress-activated protein kinase in UVC-induced phosphorylation of ATF2 in JB6 cells. Carcinogenesis 25(10): 1847-52, 2004.  Abstract 
  13. Hu J, Nakano H, Sakurai H, & Colburn NH. Insufficient p65 phosphorylation at S536 specifically contributes to the lack of NF-kappaB activation and transformation in resistant JB6 cells. Carcinogenesis 25(10): 1991-2003, 2004.  Abstract 
  14. Weber TJ, Negash S, Smallwood HS, Ramos KS, Thrall BD, & Squier TC. Calmodulin involvement in stress-activated nuclear localization of albumin in JB6 epithelial cells. Biochemistry 43(23): 7443-50, 2004.  Abstract 
  15. Ma C, Wang J, & Luo J. Activation of nuclear factor kappa B by diesel exhaust particles in mouse epidermal cells through phosphatidylinositol 3-kinase/Akt signaling pathway. Biochem Pharmacol 67(10): 1975-83, 2004.  Abstract 
  16. Hashimoto T, He Z, Ma WY, Schmid PC, Bode AM, Yang CS, & Dong Z. Caffeine inhibits cell proliferation by G0/G1 phase arrest in JB6 cells. Cancer Res 64(9): 3344-9, 2004.  Abstract 
  17. Dhar A, Hu J, Reeves R, Resar LM, & Colburn NH. Dominant-negative c-Jun (TAM67) target genes. HMGA1 is required for tumor promoter-induced transformation. Oncogene 23(25): 4466-76, 2004.  Abstract 
  18. Won YK, Ong CN, Shi X, & Shen HM. Chemopreventive activity of parthenolide against UVB-induced skin cancer and its mechanisms. C arcinogenesis 25(8): 1449-58, 2004.  Abstract 
  19. Li J, Dokka S, Wang L, Shi X, Castranova V, Yan Y, Costa M, & Huang C. Activation of aPKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6k in mouse epidermal JB6 cells. Mol Cell Biochem 255(1-2): 217-25, 2004.  Abstract