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Center For Cancer Research National Cancer Institute
JB6 Mouse Model

JB6 References 1999
  1. Bae GU, Seo DW, Kwon HK, Lee HY, Hong S, Lee ZW, Ha KS, Lee HW, Han JW. Hydrogen peroxide activates p70(S6k) signaling pathway. J Biol Chem 274: 32596- 32602, 1999.  Abstract 
  2. Bernstein LR & Walker SE. Tumor promotion resistant cells are deficient in AP-1 DNA binding, JunD DNA binding and JunD expression and form different AP-1-DNA complexes than promotion sensitive cells. Biochim Biophys Acta 1489(2-3): 263-80, 1999.  Abstract 
  3. Chen N, Ma W, Huang C, & Dong Z. Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen- activated protein kinases and apoptosis. J Biol Chem 274: 15389-15394, 1999.  Abstract 
  4. Chung JY, Huang C, Meng X, Dong Z, & Yang CS. Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells. Structure-activity relationship and mechanisms involved. Cancer Res 59: 4610-4617, 1999. Abstract 
  5. Cmarik JL, Min H, Hegamyer G, Zhan S, Matsuhashi S, Yoshinaga H & Colburn NH. Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc Natl Acad Sci USA 96: 14037-14042, 1999.  Abstract  Full Text   
  6. Ding M, Li JJ, Leonard SS, Ye JP, Shi X, Colburn NH, Castranova V, & Vallyathan V. Vanadate-induced activation of activator protein-1. Role of reactive oxygen species. Carcinogenesis 20: 663-668, 1999.  Abstract 
  7. Ding M, Dong Z, Chen F, Pack D, Ma WY, Ye J, Shi X, Castranova V, & Vallyathan V. Asbestos induces activator protein-1 transactivation in transgenic mice. Cancer Res 59: 1884-1889, 1999.  Abstract 
  8. Ding M, Shi X, Dong Z, Chen F, Lu Y, Castranova V, Vallyathan V. Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK. J Biol Chem 274: 30611-30616, 1999.  Abstract 
  9. Dong Z, Huang C, & Ma WY. PI-3 kinase in signal transduction, cell transformation, & as a target for chemoprevention of cancer. Anticancer Res 19: 3743-3747, 1999.  Abstract 
  10. Gopalakrishna R, Gundimeda U, Anderson WB, Colburn NH, & Slaga TJ. Tumor promoter benzoyl peroxide induces sulfhydryl oxidation in protein kinase C. Its reversibility is related to the cellular resistance to peroxide-induced cytotoxicity. Arch Biochem Biophys 363: 246-258, 1999.  Abstract 
  11. Huang C, Ma WY, Li J, & Dong Z. Arsenic induces apoptosis through a c-Jun NH2- terminal kinase- dependent, p53-independent pathway. Cancer Res 59: 3053-3058, 1999.  Abstract 
  12. Huang C, Ma WY, & Dong Z. The extracellular-signal-regulated protein kinases (Erks) are required for UV-induced AP-1 activation in JB6 cells. Oncogene 18: 2828-2835, 1999.  Abstract 
  13. Huang C, Li J, Ma WY, & Dong Z. JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate. J Biol Chem 274: 29672-29676, 1999.  Abstract 
  14. Jansen AP, Colburn NH and Verma, AK. Tumor promoter-induced ornithine decarboxylase gene espression occurs independently of AP-1 activation. Oncogene18: 5806-13, 1999.  Abstract 
  15. Kagoura M, Matsui C, & Morohashi M. Phytol is a novel tumor promoter on ICR mouse skin. Jpn J Cancer Res 90: 377-384, 1999.   Abstract 
  16. Li B, Gutierrez PL, Amstad P, & Blough NV. Hydroxyl radical production by mouse epidermal cell lines in the presence of quinone anti-cancer compounds. Chem Res Toxicol 12: 1042-1049, 1999.  Abstract 
  17. Pennie WD, Hegamyer GA, Young MR & Colburn NH. Specific methylation events contribute to the transcriptional repression of the mouse tissue inhibitor of metalloproteinases-3 gene (TIMP-3) in neoplastic cells. Cell Growth & Diff. 10:279-286, 1999.  Abstract 
  18. Rajesh D, Schell K, & Verma AK.  Ras mutation, irrespective of cell type and p53 status, determines a cell's destiny to undergo apoptosis by okadaic acid, an inhibitor of protein phosphatase 1 and 2A. Mol Pharmacol 56: 515-525, 1999.  Abstract 
  19. Shi X, Dong Z, Huang C, Ma W, Liu K, Ye J, Chen F, Leonard SS, Ding M, Castranova V, & Vallyathan V. The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NF-kappaB. Mol Cell Biochem 194: 63-70, 1999.  Abstract 
  20. Snawder JE. Effect of magnetic field exposure on anchorage-independent growth of a promoter-sensitive mouse epidermal cell line (JB6). Environ Health Perspect 107: 195-198, 1999.  Abstract  Full Text 
  21. Young MR, Li J-J, Rincon M, Flavell RA, Sathyanarayana BK, Hunziker R & Colburn NH. Transgenic mice demonstrate AP-1 transactivation is required for tumor promotion. Proc Natl Acad Sci USA 96: 9827-9832, 1999.  Abstract  Full Text