Access Keys:
Skip to content (Access Key - 0)

Center For Cancer Research National Cancer Institute
JB6 Mouse Model

JB6 References 1997
  1. Amstad PA, Liu H, Ichimiya M, Chang S, Berezesky IK, & Trump BF. Bcl-2 enhancement of malignant transformation in mouse epidermal JB6 cells. Mol Carcinog 20: 231-239, 1997.  Abstract 
  2. Amstad PA, Liu H, Ichimiya M, Berezesky IK, & Trump BF. Manganese superoxide dismutase expression inhibits soft agar growth in JB6 clone41 mouse epidermal cells. Carcinogenesis 18: 479-484, 1997.  Abstract 
  3. Chang PL, Lee TF, Garretson K, & Prince CW. Calcitriol enhancement of TPA-induced tumorigenic transformation is mediated through vitamin D receptor-dependent and -independent pathways. Clin Exp Metastasis 15: 580-592, 1997.  Abstract 
  4. Cmarik JL & Colburn NH. Use of mouse JB6 cells to identify molecular targets and novel agents for prevention of carcinogenesis. Proc Intl Conf on Food Factors. Chemistry & Cancer Prevention. Ohigashi H, et al (Eds), Springer-Verlag, Tokyo, 67-76, 1997.
  5. Deng X, Cao Y, Hu W, Gu H, & Yao K: [No point mutation of the 2.8 kb EcORI fragment of the nasopharyngeal carcinoma transforming gene TX in nasopharyngeal carcinoma]. Hunan I Ko Ta Hsueh Hsueh Pao 22: 102-104, 1997.  Abstract 
  6. Dong Z, Ding M, Ma W, & Colburn N. Inhibition of tumor promoter induced transformation by expression of the small GTP-binding protein rac in JB6 cells. Int J Onc 11: 157-161, 1997.  Abstract 
  7. Dong Z, Crawford HC, Lavrovsky V, Taub D, Watts R, Matrisian LM, & Colburn NH. A dominant negative mutant of Jun blocking 12-0-Tetradecanoylphorbol-13- acetate-Induced invasion in mouse keratinocytes. Mol Carcinog 19: 204-212, 1997.  Abstract 
  8. Dong Z, Ma W, Huang C, & Yang CS. Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, & theaflavins. Cancer Res 57: 4414-4419, 1997.  Abstract 
  9. Dong Z, Huang C, Brown RE, & Ma WY. Inhibition of activator protein 1 activity and neoplastic transformation by aspirin. J Biol Chem 272: 9962-9970, 1997.  Abstract 
  10. Gopalakrishna R, Chen ZH, & Gundimeda U. Selenocompounds induce a redox modulation of protein kinase C in the cell, compartmentally independent from cytosolic glutathione. Its role in inhibition of tumor promotion. Arch Biochem Biophys 348: 37-48, 1997.  Abstract 
  11. Huang C, Ma WY, Ryan CA, & Dong Z. Proteinase inhibitors I and II from potatoes specifically block UV- induced activator protein-1 activation through a pathway that is independent of extracellular signal-regulated kinases, c-Jun N-terminal kinases, & P38 kinase. Proc Natl Acad Sci USA 94: 11957-11962, 1997.  Abstract  Full Text   
  12. Huang C, Ma WY, Hanenberger D, Cleary MP, Bowden GT, & Dong Z. Inhibition of ultraviolet B-induced activator protein-1 (AP-1) activity by aspirin in AP-1-luciferase transgenic mice. J Biol Chem 272: 26325-26331, 1997.  Abstract 
  13. Huang C, Ma WY, Hecht SS, & Dong Z. Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphatidylinositol-3' kinase [published erratum appears in Cancer Res 1997 Nov 15;57(22):5198]. Cancer Res 57: 2873-2878, 1997.  Abstract 
  14. Huang C, Ma W, & Dong Z. Signal transduction through atypical PKCs, but not the EGF receptor, is necessary for UVC-induced AP-1 activation in immortal murine cells. Oncogene 14: 1945-1954, 1997.  Abstract 
  15. Huang C, Schmid PC, Ma WY, Schmid HH, & Dong Z. Phosphatidylinositol-3 kinase is necessary for 12-O- tetradecanoylphorbol-13-acetate-induced cell transformation and activated protein 1 activation. J Biol Chem 272: 4187-4194, 1997.  Abstract 
  16. Huang C, Ma WY, Ding M, Bowden GT, & Dong Z. Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminall kinase. J Biol Chem 272: 27753-27757, 1997.  Abstract 
  17. Huang C, Ma WY, Dawson MI, Rincon M, Flavell RA, & Dong Z. Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid. Proc Natl Acad Sci USA 94: 5826-5830, 1997.  Abstract  Full Text   
  18. Kim H, Pennie WD, Sun Y, & Colburn NH. Differential functional significance of AP-1 binding sites in the promoter of gene encoding mouse tissue inhibitor of metalloproteinases-3. Biochem J 324: 547-553, 1997.  Abstract  Full Text   
  19. Kiss Z, & Mukherjee JJ. Phosphocholine and sphingosine-1-phosphate synergistically stimulate DNA synthesis by a MAP kinase-dependent mechanism. FEBS Lett 412: 197-200, 1997.  Abstract 
  20. Kiss Z, Guyer B, & Dong Z. Promotion-resistant JB6 mouse epidermal cells exhibit defects in phosphatidylethanolamine synthesis and phorbol ester-induced phosphatidylcholine hydrolysis. Biochem J 323: 489-495, 1997.  Abstract 
  21. Li JJ, Westergaard C, Ghosh P and Colburn NH. Inhibitors of both NF-kappaB and AP-1 activation block neoplastic transformation response. Cancer Res 57: 3569-3576, 1997.  Abstract 
  22. Nakamura Y, Kawase I, Harada S, Matsuda M, Honma T, & Tomita I. Antitumor- promoting effects of tea aqueous nondialysates in mouse epidermal JB6 cells. In Ohigashi H, Osawa T, Terao T, Watanabe S, Yoshikawa T (Eds), Food Factors for Cancer Prevention, Tokyo, Springer-Verlaag, 1997, pp 138-141.
  23. Pennie WD, Sun Y, Kim H, & Colburn NH. Differential expression of TIMP-3 during neoplastic progression in the mouse JB6 model system. In Liang P & Pardee AB (Eds). Diff Display, Meth, & Protocols, Totowa, NJ, Humana Press, 85: 249-261, 1997.  Pub Med link   
  24. Saffer JD, Chen G, Colburn NH, & Thurston SJ. Power frequency magnetic fields do not contribute to transformation of JB6 cells. Carcinogenesis 18: 1365-1370, 1997.  Abstract 
  25. Strickland J, Sun Y, Dong Z & Colburn NH. Grafting assay distinguishes promotion sensitive from promotion resistant JB6 cells. Carcinogenesis 18: 1135-1138, 1997.  Abstract