2021 Project Z Numbers

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Lab/BranchPI NameZ NumberProject Title
Cancer and Developmental Biology LaboratoryAcharya, JairajZIA BC 010331Phospholipid and Sphingolipid Signaling in Drosophila
Cancer and Developmental Biology LaboratoryAcharya, JairajZIA BC 011187Sphingolipid Signaling in Mammals
Laboratory of Molecular BiologyAdhya, SankarZIA BC 008751Regulation of Gene Transcription
Laboratory of Molecular BiologyAdhya, SankarZIA BC 010017Use of Bacteriophages to Prevent, Diagnose, and Treat Diseases
Developmental Therapeutics BranchAladjem, MiritZIA BC 010411Initiation of DNA Replication in Mammalian Cells
Laboratory of PathologyAldape, KennethZIA BC 011846Single-cell DNA methylation analysis of human cancer
Laboratory of PathologyAldape, KennethZIA BC 011847Development and validation of a predictor of meningioma recurrence
Laboratory of PathologyAldape, KennethZIA BC 011850Genomic Biomarkers of Cancer
Laboratory of Molecular BiologyAlewine, ChristineZIA BC 011652Mesothelin-targeted immunotoxins in Pancreatic Cancer
Laboratory of Molecular BiologyAlewine, ChristineZIA BC 011886First in Human Trials of ProAgio, a Cytotoxin
Laboratory of Molecular BiologyAlewine, ChristineZIA BC 012041Rare Exocrine Tumors of the Pancreas
Laboratory of Molecular BiologyAlewine, ChristineZIE BC 011653Clinical Support
Laboratory of Integrative Cancer ImmunologyAltan-Bonnet, GregoireZIA BC 011726Phenotypic variability within isogenic population of lymphocytes
Laboratory of Integrative Cancer ImmunologyAltan-Bonnet, GregoireZIA BC 011728Cytokine coordination of collective immune responses against tumors
Laboratory of Integrative Cancer ImmunologyAltan-Bonnet, GregoireZIA BC 011781Dynamics of hematopoietic differentiation
Laboratory of Integrative Cancer ImmunologyAltan-Bonnet, GregoireZIA BC 011807Immunophenotyping by CyTOF and machine learning
Laboratory of Integrative Cancer ImmunologyAltan-Bonnet, GregoireZIA BC 012007Dynamics of viral infection
Laboratory of Human CarcinogenesisAmbs, StefanZIA BC 010499Maryland Prostate Cancer Case-Control Study
Laboratory of Human CarcinogenesisAmbs, StefanZIA BC 010624The Molecular Profile of Prostate Tumors in African-American Men
Laboratory of Human CarcinogenesisAmbs, StefanZIA BC 010887Novel Markers for Disease Outcome in Breast Cancer
Laboratory of Cell BiologyAmbudkar, SureshZIA BC 010030Biochemical Analysis of Multidrug Resistance-linked Transport Proteins
Laboratory of Cancer ImmunometabolismAnderson, StephenZIA BC 010013Molecular Studies of Cellular Cytotoxicity
Women's Malignancies BranchAnnunziata, ChristinaZIA BC 011054Nuclear Factor-kappaB in Ovarian Cancer
Women's Malignancies BranchAnnunziata, ChristinaZIA BC 011584Clinical trials in womens cancers
Women's Malignancies BranchAnnunziata, ChristinaZIA BC 011775Immune cell control of ovarian cancer
Genetics BranchAplan, PeterZIA BC 010982Collaborative Pathways that Lead to Leukemia
Genetics BranchAplan, PeterZIA BC 010983Pre-clinical Studies of Therapy for Myelodysplastic Syndrome
Genetics BranchAplan, PeterZIA SC 010378Activation of Proto-Oncogenes by Chromosomal Translocation
Genetics BranchAplan, PeterZIA SC 010379Mechanisms of Chromosomal Translocation
Genitourinary Malignancies BranchApolo, AndreaZIA BC 011351Bladder Cancer Program
Genitourinary Malignancies BranchApolo, AndreaZIA BC 011594Targeting the MET Pathway in Urothelial Carcinoma
Genitourinary Malignancies BranchApolo, AndreaZIA BC 011928Rare GU tumors projects
Laboratory of Cell BiologyAppella, EttoreZIA BC 005599Tumor Suppressor Protein, p53
Laboratory of Cell BiologyAppella, EttoreZIA BC 011197Regulation and Function of WIP1 Phosphatase and its Role in Tumor Cells
Laboratory of Receptor Biology and Gene ExpressionArda, HaticeZIA BC 011798Identification of genomic regulatory elements in pancreas cells
Neuro-Oncology BranchArmstrong, TerriZIA BC 011768Natural History and Specimen Banking for Patients with CNS Tumors
Neuro-Oncology BranchArmstrong, TerriZIA BC 011837Outcomes and Risk of Rare Tumors
Neuro-Oncology BranchArmstrong, TerriZIA BC 011893Behavioral Correlates in Mouse Model of CNS radiation-induced hypersomnia
Laboratory of Immune Cell BiologyAshwell, JonathanZIA BC 011264Glucocorticoids and T cell development and function
Laboratory of Immune Cell BiologyAshwell, JonathanZIA BC 011715T cell receptor proximal signaling
Laboratory of Immune Cell BiologyAshwell, JonathanZIA BC 011976TNF and inflammation
Laboratory of Biochemistry and Molecular BiologyBai, YawenZIA BC 010808Chromatin structure and dynamics
Chemical Biology LaboratoryBarchi, JosephZIA BC 010451Carbohydrate Antigen-bearing Nanoparticles for Antitumor Therapy
Chemical Biology LaboratoryBarchi, JosephZIA BC 011232A Glycopeptide from Interstitial Cystitis Patients as a Novel Anticancer Lead
Laboratory of PathologyBarr, FredericZIA BC 011378Studies of amplification in rhabdomyosarcoma
Laboratory of PathologyBarr, FredericZIA BC 011387Studies of gene fusions in rhabdomyosarcoma
Laboratory of PathologyBarr, FredericZIA BC 011423Epigenetic studies in rhabdomyosarcoma
Laboratory of PathologyBarr, FredericZIE BC 011384Anatomic Pathology Residency Program
Laboratory of Cellular and Molecular BiologyBarr, ValarieZIC BC 010978Confocal Core for the Laboratory of Cellular and Molecular Biology
Genetics BranchBasrai, MuniraZIA BC 010822Molecular Determinants of Chromosome Transmission and Cell Cycle Regulation
Laboratory of Cell BiologyBatista, PedroZIA BC 011766Regulation of RNA biogenesis and function by RNA modifications
Vaccine BranchBerzofsky, JayZIA BC 011941Studies of the SARS-CoV-2 Spike Protein
Vaccine BranchBerzofsky, JayZIA BC 012054Vaccine strategies for HIV/AIDS
Vaccine BranchBerzofsky, JayZIA SC 004020Vaccine and immunotherapy strategies for cancer and viruses causing cancer
Molecular Targets ProgramBeutler, JohnZIA BC 011469Building Libraries with Chemical Diversity for Screening
Molecular Targets ProgramBeutler, JohnZIA BC 011470Development of Natural Product Leads as Anticancer Therapeutics
Surgery BranchBeyer, RachelZIC BC 010989Clinical production of viral vectors for cancer gene therapy
Surgery BranchBeyer, RachelZIC BC 012049QC and Release Testing of Clinical Vector and Cell Gene Therapy Products
Surgery BranchBeyer, RachelZIC BC 012051Characterization of lentivirus for use in individualized cell-gene therapy
Laboratory of Genome IntegrityBhandoola, AvinashZIA BC 011633T cell Development and Regeneration
Office of the Clinical DirectorBilusic, MarijoZIE BC 010843NIH Hematology Oncology Fellowship Program
Laboratory of Immune Cell BiologyBosselut, RemyZIA BC 010671Genetic Analysis of T-cell Differentiation
Urologic Oncology BranchBottaro, DonaldZIA BC 011095Hypoxia and Tyrosine Kinase Signaling Integration in Urologic Cancers
Urologic Oncology BranchBottaro, DonaldZIA BC 011124Oncogenic Met Signaling in Urologic Malignancies
Laboratory of Cell and Developmental SignalingBrognard, JohnZIA BC 011690Novel Tumor Suppressing Kinases in Cancer
Laboratory of Cell and Developmental SignalingBrognard, JohnZIA BC 011691Oncogenic Kinases in Cancer
Office of the DirectorBronez, MelissaZIJ BC 011285CCR Education and Outreach
Office of the DirectorBrownell, IsaacZIA BC 011393Development and regulation of stem cell lineages in skin
Office of the DirectorBrownell, IsaacZIA BC 011394Molecular pathogenesis and therapy innovation for Merkel cell carcinoma
Office of the DirectorBrownell, IsaacZIA BC 011450Clinical treatment of advanced Merkel cell carcinoma
Office of the DirectorBrownell, IsaacZIA BC 011930Investigation of skin cancer and skin disease
Laboratory of Cellular OncologyBuck, ChristopherZIA BC 011090Molecular biology of human polyomaviruses
Laboratory of Cellular OncologyBuck, ChristopherZIA BC 011460BKV and JCV vaccine development
Laboratory of Human CarcinogenesisBudhu, AnuradhaZIA BC 011870Liver Cancer Program
Chemical Biology LaboratoryBurke, TerrenceZIA BC 006198Inhibitors of Tyrosine Kinase-Dependent Signaling as Anti-Cancer Agents
Chemical Biology LaboratoryBurke, TerrenceZIA BC 007363Design and Synthesis of HIV Integrase as Potential Anti-AIDS Drugs
Laboratory of MetabolismBustin, MichaelZIA BC 004496Chromosomal Proteins and Chromosomal Functions
Laboratory of MetabolismBustin, MichaelZIA BC 011154Biological Functions of Chromosomal Proteins
Experimental Transplantation and Immunotherapy BranchBuxbaum, NataliyaZIA BC 011725Immunometabolism and metabolic imaging of graft-versus-host disease
Experimental Transplantation and Immunotherapy BranchBuxbaum, NataliyaZIA BC 011777Stable Water Isotope Labeling for Imaging of Rapidly Proliferating Cells
Experimental Transplantation and Immunotherapy BranchBuxbaum, NataliyaZID BC 011729Chronic graft-versus-host disease in children and young adults
Center for Structural BiologyByrd, R. AndrewZIA BC 011131Investigation of Protein-Protein Interactions in the ERAD Ubiquitylation Pathway
Center for Structural BiologyByrd, R. AndrewZIA BC 011132Methods Development
Center for Structural BiologyByrd, R. AndrewZIA BC 011419Structural Biology of GTPase Activating Proteins
Genetics BranchCalzone, KathyZIC BC 011931Genomic Data Sharing
Genetics BranchCalzone, KathyZID BC 011908Clinical Cancer Genomics Program
Genetics BranchCalzone, KathyZIE BC 011912Genomic Competency Initiative
Radiation Oncology BranchCamphausen, KevinZIA SC 010372Pre-clinical Development of Radiation Sensitizers for Patients with Glioblastoma
Radiation Oncology BranchCamphausen, KevinZIA SC 010373The Synergy Between Radiotherapy and Molecularly Targeted Agents
Radiation Oncology Branch (OOC)Camphausen, KevinZIC BC 010991Radiation Oncology Branch - Microarray Facility
Radiation Oncology Branch (OOC)Camphausen, KevinZID BC 010990Radiation Oncology Branch - Radiation Clinic
Genetics BranchCao, LiangZIC BC 010981Biomarker Investigations for Clinical Trials
Genetics BranchCao, LiangZIC BC 012031Omics Technology facility
Genetics BranchCaplen, NatashaZIA BC 011704Discovery of genes required for expression or activity of fusion oncogenes
Laboratory of Cancer Biology and GeneticsCappell, StevenZIA BC 011830Control of cell cycle commitment by APC-C-Cdh1
Laboratory of Cancer Biology and GeneticsCappell, StevenZIA BC 011832Study cell cycle regulation in dormant tumor cells
Laboratory of Cancer ImmunometabolismCarrell, JeffreyZIC BC 011236CCR-Frederick Flow Cytometry Core
Laboratory of Integrative Cancer ImmunologyCarrington, MaryZIA BC 010791Effects of genetic polymorphism in MHC, KIR, and related loci on human disease
Laboratory of Integrative Cancer ImmunologyCarrington, MaryZIA BC 010792Molecular genetics and population studies of the KIR and HLA gene complexes
Laboratory of Integrative Cancer ImmunologyCarrington, MaryZIA BC 011949Host genetic resistance to COVID-19
Basic Research Laboratory BethesdaChattoraj, DhrubaZIA BC 010277Mechanisms of Chromosome Maintenance in Bacteria
Laboratory of Biochemistry and Molecular BiologyChen, ChongyiZIA BC 011884The dynamics of chromatin topology in human cells
Thoracic Surgery BranchChen, HaobinZIA BC 011787Predictive biomarker of BET bromodomain inhibitor in Small cell lung cancer
Thoracic Surgery BranchChen, HaobinZIA BC 011839Developing an Effective BET bromodomain inhibitor Drug Combo to Target SCLC
Laboratory of Molecular BiologyCheng, Sheue-yannZIA BC 008752Thyroid Hormone Nuclear Receptors in Health and Disease
Laboratory of Molecular BiologyCheng, Sheue-yannZIA BC 011191Preclinical Mouse Models of Thyroid Cancer
Radiation Biology BranchCherukuri, MuraliZIA BC 010476Time Domian Electron Paramagnetic Resonance Imaging
Radiation Biology BranchCherukuri, MuraliZIA BC 010477Overhauser Enhanced Magnetic Resonance Imaging (OMRI)
Laboratory of PathologyChinquee, JosephZIC BC 010687Histology Core Laboratory
Laboratory of PathologyChinquee, JosephZIC BC 011731Tissue Procurement, Processing Facility and Biorepository
Laboratory of PathologyChinquee, JosephZID BC 010686Clinical Operations for Laboratory of Pathology
Molecular Imaging BranchChoyke, PeterZIA BC 010655Prostate Cancer Imaging
Molecular Imaging BranchChoyke, PeterZIA BC 010656Growth Factor Imaging and Photoimmunotherapy
Molecular Imaging BranchChoyke, PeterZIA BC 010657Cellular In vivo Imaging
Molecular Imaging BranchChoyke, PeterZIA BC 010668Instrumentation for microSPECT and microPET imaging
Office of the DirectorChoyke, PeterZIA BC 011872PSMA-PET Imaging of High Risk Prostate Cancer-Cures
Radiation Oncology BranchCitrin, DeborahZIA BC 010850Mechanisms of Normal Tissue Toxicity From Irradiation
Radiation Oncology BranchCitrin, DeborahZIA BC 011552Targeting mechanisms of radiation resistance
Radiation Oncology BranchCitrin, DeborahZIA BC 011762Screening to identify protectors and mitigators of Radiation GI Syndrome
Radiation Oncology BranchColeman, C. NormanZIA BC 010670Radiation-induced molecular targets
HIV DRP Retroviral Replication LaboratoryCompton, AlexZIA BC 011756An Intrinsic Link between the Metabolic and Antiviral States of the Cell
HIV DRP Retroviral Replication LaboratoryCompton, AlexZIA BC 011778Quantitative Single-Cell Assessment of Lentivirus Susceptibility Determinants
HIV DRP Retroviral Replication LaboratoryCompton, AlexZIA BC 011779Mechanisms of Virus Entry into Cells and Antiviral Barriers Limiting Entry
HIV DRP Retroviral Replication LaboratoryCompton, AlexZIA BC 011935CRISPR-Cas9 Screen for SARS-CoV-2 Host Dependency Factors
HIV DRP Retroviral Replication LaboratoryCompton, AlexZIA BC 011967Deciphering the Double-Edged Role of IFITM3 during SARS-CoV-2 Infection
Genetics BranchConner, ElizabethZIC BC 011623CCR Genomics Core
Office of the DirectorCowen, EdwardZIA BC 011549Chronic graft-versus-host disease
Office of the DirectorCowen, EdwardZIA BC 011550Anakinra for neutrophilic pustular skin disease
Office of the DirectorCowen, EdwardZID BC 011317Dermatology Consultation Service
Urologic Oncology BranchCrooks, DanielZIC BC 011932Metabolomics Core
Office of the DirectorCuster, MaryZIG BC 010856Basic and Preclinical Animal Models in support of Cancer and HIV-AIDS Research
Cancer and Developmental Biology LaboratoryDaar, IraZIA BC 010006Mechanisms of Cross-talk Between EphrinB and Alternate Signaling Pathways
Cancer and Developmental Biology LaboratoryDaar, IraZIA BC 010958Signaling Mechanisms of EphrinB1 in Cell Adhesion, Migration and Invasion
Genitourinary Malignancies BranchDahut, WilliamZIA SC 010098The Evaluation of Novel Therapeutics for Genitourinary Malignancies
Mouse Cancer Genetics ProgramDai, ChengkaiZIA BC 011767Preservation of Proteomic Stability and Promotion of Protein Lipidation by HSF1
Laboratory of Receptor Biology and Gene ExpressionDalal, YaminiZIA BC 011206Role of histone variants in aging and cancer
Laboratory of Receptor Biology and Gene ExpressionDalal, YaminiZIA BC 011207Biomechanical properties of chromatin in cancer and normal cells
Laboratory of Receptor Biology and Gene ExpressionDalal, YaminiZIA BC 011209Formation of Centromeres in vivo
Surgery BranchDanforth, DavidZIA SC 006663Molecular Characterization of Breast Duct Epithelium at Risk for Breast Cancer
Cancer and Developmental Biology LaboratoryDavies, ErinZIA BC 012009Mechanisms underlying establishment of regeneration competence
Cancer and Developmental Biology LaboratoryDavies, ErinZIA BC 012055Stem cell ontogeny and dynamics in Macrostomum lignano
Developmental Therapeutics BranchDoroshow, JamesZIA BC 010677NADPH Oxidases as Novel Targets for Cancer Therapy
Developmental Therapeutics BranchDoroshow, JamesZIA BC 011078Phase 0-1 Clinical Trials
Molecular Targets ProgramDu, LinZIA BC 011568Natural Products Discovery and Characterization Through Network Collaborations
Laboratory of Cancer Biology and GeneticsDuBois, WendyZIC BC 011047Animal Model and Genotyping Core Support Facility
Laboratory of Cell BiologyDurell, StewartZIA BC 011379Inhibitor Development Against the Wip1 Phosphatase
Laboratory of Cell BiologyDurell, StewartZIC BC 011075Molecular Modeling of the Human P-glycoprotein Transporter Protein
Laboratory of Cell BiologyDurell, StewartZIC BC 011077Molecular Modeling of Interactions Regulating the Activity of the p53 Protein
Laboratory of Cell BiologyDurell, StewartZIC BC 011380HIV NCp7 inhibitors and Multivalent Inhibition of Membrane Receptors
Laboratory of Cell BiologyDurell, StewartZIC BC 011724Effects of Cytosine Modifications on Transcription Factor Binding
Laboratory of Cancer ImmunometabolismDurum, ScottZIA BC 009287Cytokines and T Cell Development
Laboratory of Cancer ImmunometabolismDurum, ScottZIA BC 011150Chronic Inflammation and Carcinogenesis
Molecular Imaging BranchEscorcia, FreddyZIA BC 011800Engineering HCC-selective PET agent
Vaccine BranchFelber, BarbaraZIA BC 010334Conserved Element DNA Vaccine
Vaccine BranchFelber, BarbaraZIA BC 010350Prevention of AIDS
Vaccine BranchFelber, BarbaraZIA BC 011940COVID-19 vaccine development research
Genitourinary Malignancies BranchFigg, WilliamZIA BC 010453Genetics and Molecular Mechanisms of Prostate Cancer
Genitourinary Malignancies BranchFigg, WilliamZIA BC 010547Drug Development for Prostate Cancer and other Metastatic Processes
Office of the Clinical DirectorFigg, WilliamZIA BC 010627Clinical Pharmacogenetics
Office of the Clinical DirectorFigg, WilliamZIA BC 011974COVID-19 Genetics and Drug Development
Office of the Clinical DirectorFigg, WilliamZIA BC 011996Clinical Pharmacology & Drug-Drug Interactions in HIV-Associated Malignancy
Genitourinary Malignancies BranchFigg, WilliamZIA SC 006538Development of Angiogenesis Inhibitors
Office of the Clinical DirectorFigg, WilliamZIC SC 006536Biospecimen Processing and Biorepository
Office of the Clinical DirectorFigg, WilliamZIC SC 006537Using Clinical Pharmacology Principles to Develop New Anticancer Therapies
Laboratory of PathologyFilie, ArmandoZIC BC 011052Cytopathology Core
Laboratory of Molecular BiologyFitzGerald, DavidZIA BC 008757Bio-Therapies for the Treatment of Cancer
Experimental Transplantation and Immunotherapy BranchFlomerfelt, FrancisZIC BC 010934Immune reconstitution following autologous and allogeneic stem cell transplant
Experimental Transplantation and Immunotherapy BranchFlomerfelt, FrancisZIC BC 011029Preclinical development and clinical monitoring of adoptive immune therapy
Vaccine BranchFranchini, GenoveffaZIA BC 005645Role of the HTLV-1A and HTLV1-C inflammatory profile in disease
Vaccine BranchFranchini, GenoveffaZIA BC 011126Development of rationally designed HIV vaccines
Vaccine BranchFranchini, GenoveffaZIA BC 012025Phase I HIV vaccine trial with DNA/ALVAC-HIV gp120 delta V1 vaccines
HIV DRP Retroviral Replication LaboratoryFreed, EricZIA BC 010778HIV-1 Maturation
HIV DRP Retroviral Replication LaboratoryFreed, EricZIA BC 011720Gag Trafficking, Assembly, and Release
HIV DRP Retroviral Replication LaboratoryFreed, EricZIA BC 011721Envelope Glycoprotein Incorporation and Function
HIV DRP Retroviral Replication LaboratoryFreed, EricZIA BC 011968Antagonism of Coronavirus Spike Proteins by Cellular Host Factors
Neuro-Oncology BranchGilbert, MarkZIA BC 011640Exploring the Therapeutic Potential of Stem Cell Biology in Gliomas
Neuro-Oncology BranchGilbert, MarkZIA BC 011643Rare Central Nervous System Cancers Initiative
Neuro-Oncology BranchGilbert, MarkZIA BC 011647Identifying New Glioma-Associated Tumor Suppressors and Oncogenes
Neuro-Oncology BranchGilbert, MarkZIA BC 011714Translational Immunology
Neuro-Oncology BranchGilbert, MarkZIA BC 011784Bioinformatics: Characterizing Brain Tumor Data
Office of the DirectorGilbert, MarkZIA BC 011853CONNECT: Comprehensive Oncology Network Evaluating Rare CNS Tumors - Cures
Neuro-Oncology BranchGilbert, MarkZIC BC 011641Pre-clinical Translational Research Facility
Neuro-Oncology BranchGilbert, MarkZID BC 011642Brain Tumor Clinical and Clinical Research Program
Chemical Biology LaboratoryGildersleeve, JeffreyZIA BC 010675Development of a Carbohydrate Microarray
Chemical Biology LaboratoryGildersleeve, JeffreyZIA BC 010740Carbohydrate Microarray Profiling of Glycan-Binding Antibodies and Lectins
Chemical Biology LaboratoryGildersleeve, JeffreyZIA BC 011055Serum Antibody Profiling with a Carbohydrate Microarray
Pediatric Oncology BranchGlod, JohnZID BC 011517Pediatric Oncology Branch Behavioral Science Core
Pediatric Oncology BranchGlod, JohnZIE BC 011516Pediatric Oncology Branch Clinical Care and Education
Office of Science and Technology ResourcesGoldstein, DavidZIC BC 011331CCR Sequencing Facility
Office of the DirectorGoldstein, DavidZIC BC 011532CCR Collaborative Bioinformatics Resource
Office of Science and Technology ResourcesGoldstein, DavidZIK BC 010857Science and Technology Resources
Laboratory of Integrative Cancer ImmunologyGoldszmid, RominaZIA BC 011670Role of the microbiota in regulating the mononuclear phagocyte system
RNA Biology LaboratoryGonatopoulos Pournatzis, ThomasZIA BC 012019Investigating the regulation of alternative splicing and its role in disease
RNA Biology LaboratoryGonatopoulos Pournatzis, ThomasZIA BC 012033High-throughput phenotypic screening for functionally characterizing alt. exons
Laboratory of MetabolismGonzalez, FrankZIA BC 005562Xenobiotic receptors
Laboratory of MetabolismGonzalez, FrankZIA BC 005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers
Laboratory of Cell BiologyGottesman, MichaelZIA BC 005598Genetic Analysis of the Multidrug Resistance Phenotype in Tumor Cells
Laboratory of Cell BiologyGottesman, MichaelZIA BC 010830Mechanisms of non-classical multidrug resistance in cancer
Laboratory of Cell BiologyGottesman, MichaelZIA BC 012052Zebrafish model of blood-brain barrier to improve drug delivery to the brain
Laboratory of Molecular BiologyGottesman, SusanZIA BC 008714Bacterial Functions Involved in Cell Growth Control
Laboratory of Molecular BiologyGottesman, SusanZIA BC 011203Proteolysis and Regulation of Bacterial Cell Growth Control
Experimental Transplantation and Immunotherapy BranchGress, RonaldZIA BC 010525Immune Reconstitution
Experimental Transplantation and Immunotherapy BranchGress, RonaldZIA BC 010960ETIB Clinical Trials
Experimental Transplantation and Immunotherapy BranchGress, RonaldZID BC 010963ETIB Clinical Research Core
Thoracic and GI Malignancies BranchGreten, TimZIA BC 011343Clinical protocols for the treatment of gastrointestinal cancer
Thoracic and GI Malignancies BranchGreten, TimZIA BC 011344Immune suppressor mechanisms in patients with GI cancer
Thoracic and GI Malignancies BranchGreten, TimZIA BC 011345Analysis of cancer-related immune suppressor mechanisms in mice
Office of the DirectorGreten, TimZIA BC 011855Center for Cell-based Therapy - Cures
Thoracic and GI Malignancies BranchGreten, TimZIA BC 011947The effect of hydroxychloroquine treatment on immune checkpoint inhibitors
Laboratory of Biochemistry and Molecular BiologyGrewal, ShivZIA BC 010523RNAi and Epigenetic Control of Higher-Order Chromatin Assembly
Laboratory of Biochemistry and Molecular BiologyGrewal, ShivZIA BC 011208Roles of Chromatin-modifying Factors in Epigenetic Control of the Genome
RNA Biology LaboratoryGu, ShuoZIA BC 011566Mechanism, Regulation and Application of miRNA pathway in cancer
Genitourinary Malignancies BranchGulley, JamesZIA BC 010666Cancer Therapy Clinical Trials Using Novel Recombinant Vaccines
Genitourinary Malignancies BranchGulley, JamesZIA BC 010945Clinical trials employing cancer vaccine combination therapies
Office of the DirectorGulley, JamesZIA BC 011871T-Cell Receptor Gene Therapy for Human Cancers-Cures
Office of the Clinical DirectorGulley, JamesZID BC 011543Medical Oncology Service Clinical Core
Office of the Clinical DirectorGulley, JamesZID BC 011683Medical Oncology HIV-AIDS Clinical Research
Laboratory of Receptor Biology and Gene ExpressionHager, GordonZIA BC 005450Chromatin Structure and Gene Expression
Laboratory of Receptor Biology and Gene ExpressionHager, GordonZIA BC 010027Function of Steroid Receptors in Subcellular Compartments
Laboratory of Receptor Biology and Gene ExpressionHager, GordonZIA BC 010308In vivo Imaging Analysis of Steroid-Nuclear Receptor Function
Laboratory of Receptor Biology and Gene ExpressionHager, GordonZIA BC 010646Chromatin Remodeling Proteins
Surgery BranchHalas, HyunmiZIC BC 010905Surgery Branch Cell Prep Core
Surgery BranchHalas, HyunmiZIC BC 011569Cell Production Core Facility
Cancer Data Science LaboratoryHannenhalli, SridharZIA BC 011964Transcriptomic origins of cancer
Cancer Data Science LaboratoryHannenhalli, SridharZIA BC 011978Developmental origins of Cancer
Cancer Data Science LaboratoryHannenhalli, SridharZIA BC 011979Identifying non-coding drivers of cancer
Cancer Data Science LaboratoryHannenhalli, SridharZIA BC 011981Machine learning, network-based models for gene expression, activity, function
Cancer Data Science LaboratoryHannenhalli, SridharZIA BC 011984Gene interactions in cancer
Laboratory of Human CarcinogenesisHarris, CurtisZIA BC 011492Precision Medicine of Cancer
Laboratory of Human CarcinogenesisHarris, CurtisZIA BC 011496p53, Aging, and Cancer
Thoracic and GI Malignancies BranchHassan, RaffitZIA BC 010816Immunotherapy for Malignant Mesothelioma and Lung Cancer
Thoracic and GI Malignancies BranchHassan, RaffitZID BC 011540Thoracic and Gastrointestinal Malignancies Branch Clinical Core
Office of the DirectorHenderson, DarrenZII BC 011234CCR New Space Activation
Surgical Oncology ProgramHernandez, JonathanZIA BC 011759Interrogating the molecular underpinnings of metastatic colonization
Surgical Oncology ProgramHernandez, JonathanZIA BC 011861Evaluating outcomes for patients with primary-metastatic gastrointestinal cancer
Pediatric Oncology BranchHeske, ChristineZIA BC 011745Development of biologic based therapies for rhabdomyosarcoma
Pediatric Oncology BranchHeske, ChristineZIA BC 011774Development and translation of novel therapies for pediatric sarcoma
Laboratory of PathologyHewitt, StephenZIC BC 011638Experimental Pathology Laboratory (EPL)
Immune Deficiency and Cellular Therapy ProgramHickstein, DennisZIA BC 010870Hematopoietic Stem Cell Transplant for GATA2 Deficiency
Immune Deficiency and Cellular Therapy ProgramHickstein, DennisZIA BC 011994Allogeneic Hematopoietic Transplantation for Primary Immunodeficiency Diseases
Immune Deficiency and Cellular Therapy ProgramHickstein, DennisZIA SC 010384Hematopoietic Stem Cell Gene Therapy for Leukocyte Adhesion Deficiency
Genitourinary Malignancies BranchHinrichs, ChristianZIA BC 011479T-cell receptor gene therapy for cancer
Laboratory of Molecular BiologyHo, MitchellZIA BC 010891Development of new antibody-based cancer therapies
Laboratory of Molecular BiologyHo, MitchellZIA BC 011943Development of neutralizing nanobodies against SARS-CoV-2
Laboratory of Molecular BiologyHo, MitchellZIC BC 011891Antibody Engineering Program
Thoracic Surgery BranchHoang, ChuongZIA BC 011657microRNA-based & novel molecular therapeutics in thoracic cancers
Experimental Immunology BranchHodes, RichardZIA BC 009265Analysis of the T Cell Repertoire
Experimental Immunology BranchHodes, RichardZIA BC 009281Receptor Mediated T and B Cell Activation
Experimental Immunology BranchHodes, RichardZIA BC 009405Regulation of Lymphocyte Proliferation and Replicative Capacity
Laboratory of Tumor Immunology and BiologyHodge, JamesZIA BC 010661Vaccine and Drug Combination Therapy for Human Cancers
Laboratory of Tumor Immunology and BiologyHodge, JamesZIA BC 010975Vaccine and radiation for the therapy of human cancers
HIV DRP Retroviral Replication LaboratoryHu, Wei-ShauZIA BC 010504Understanding Retroviral Reverse Transcription, Recombination, and Replication
HIV DRP Retroviral Replication LaboratoryHu, Wei-ShauZIA BC 010506Defining Mechanisms of HIV-1 Gag:RNA Interactions and Virus Assembly
HIV DRP Retroviral Replication LaboratoryHu, Wei-ShauZIA BC 010814Elucidating the Regulation of HIV RNA Functions: Translation & Genome Packaging
HIV DRP Retroviral Replication LaboratoryHu, Wei-ShauZIA BC 011969Development of Cell-based Assays to Identify SARS-CoV-2 Protease Inhibitor
Laboratory of Cancer ImmunometabolismHu, YinlingZIA BC 011212Functions of IKK alpha in Skin Homeostasis and Skin Tumorigenesis
Laboratory of Cancer ImmunometabolismHu, YinlingZIA BC 011391Role of IKK alpha in lung cancer development
Laboratory of Cancer ImmunometabolismHu, YinlingZIA BC 011422Role of IKK alpha in lymphoid organ development
Laboratory of Cancer Biology and GeneticsHuang, JingZIA BC 011158Stress responses in embryonic stem cells
Laboratory of Cancer Biology and GeneticsHuang, JingZIA BC 011504Vulnerabilities in osteosarcoma and breast cancer
HIV DRP Retroviral Replication LaboratoryHughes, StephenZIA BC 010481HIV-1 Reverse Transcriptase
HIV DRP Retroviral Replication LaboratoryHughes, StephenZIA BC 011426HIV-1 Integrase
Laboratory of Cancer Biology and GeneticsHunter, KentZIA BC 011255Genetic Modifiers of Initiation and Progression of Mammary Cancer
Laboratory of Human CarcinogenesisHussain, S. PerwezZIA BC 011162Integrative Molecular Profiling of Human Pancreatic Cancer
Laboratory of Human CarcinogenesisHussain, S. PerwezZIA BC 011185Role of Immune and Inflammation Mediators in Progression of Pancreatic Cancer
Laboratory of Cellular and Molecular BiologyIglesias-Bartolome, RamiroZIA BC 011763Signaling pathways regulating stem cell fate decisions
Laboratory of Cellular and Molecular BiologyIglesias-Bartolome, RamiroZIA BC 011764G-protein-coupled receptor signaling in cancer development and treatment
Genitourinary Malignancies BranchIshii, KazusaZIA BC 012045TCR engineered T cell therapies for hematologic malignancies
Laboratory of PathologyJaffe, ElaineZIA BC 011070Hematopathology Diagnosis
Laboratory of PathologyJaffe, ElaineZIA SC 000550Lymphoma Disease Discovery and Definition
Laboratory of PathologyJaffe, ElaineZIE BC 011241Hematopathology Fellowship
Laboratory of Cell BiologyJenkins, LisaZIC BC 011430CPTR - Mass Spectrometry Unit
Center for Structural BiologyJi, XinhuaZIA BC 010326Biomolecular Structure and Mechanism, Structure-Based Drug Design
Cancer Data Science LaboratoryJiang, PengZIA BC 011889Data-driven inference of regulators for cytokine-mediated tumor killing
Cancer Data Science LaboratoryJiang, PengZIA BC 011890Computational approaches for the analyses of spatial profiling technologies
Mouse Cancer Genetics ProgramJohnson, PeterZIA BC 010328Role of C/EBP transcription factors in cell growth and tumorigenesis
Laboratory of PathologyJones, JenniferZIA BC 011502Characterization of Biological Nanoparticle Subsets
Laboratory of PathologyJones, JenniferZIA BC 011503Discovery of Tumor and Treatment Response Biomarkers
Laboratory of PathologyJones, JenniferZIA BC 011942Translational Nanobiology Approaches to SARS-CoV2
Experimental Transplantation and Immunotherapy BranchKanakry, ChristopherZIA BC 011659Deciphering the efficacy of posttransplant cyclophosphamide in BMT
Pediatric Oncology BranchKaplan, RosandraZIA BC 011332Tumor Microenvironment in Cancer Progression
Pediatric Oncology BranchKaplan, RosandraZIA BC 011334Biomarkers and Therapeutic Targets in Tumor Microenvironment and Metastasis
Laboratory of Receptor Biology and Gene ExpressionKarpova, TatianaZIC BC 011571Transcription factor mobility
Laboratory of Receptor Biology and Gene ExpressionKarpova, TatianaZIC BC 011574LRBGE Optical Microscopy Core
RNA Biology LaboratoryKashlev, MikhailZIA BC 010795Mechanisms of transcription pausing and fidelity in prokaryotes and eukaryotes
HIV DRP Host-Virus Interaction BranchKearney, MaryZIA BC 011681Dynamics and Genetics of HIV Proviruses before and during Antiretroviral Therapy
HIV DRP Host-Virus Interaction BranchKearney, MaryZIA BC 011697Effects of Antiretroviral Therapy on Transcriptional Activity of HIV Proviruses
HIV DRP Host-Virus Interaction BranchKearney, MaryZIA BC 011698Impact of Interventions on Clonally Expanded Proviruses and Their RNA Expression
HIV DRP Host-Virus Interaction BranchKearney, MaryZIA BC 011699Ultrasensitive Single-Genome Sequencing to Study HIV Transmission and Evolution
HIV DRP Host-Virus Interaction BranchKearney, MaryZIA BC 011995Assessment of SARS-Coronavirus-2 Levels and Genetics in Vivo
Office of Science and Technology ResourcesKedei, NoemiZIC BC 011434Collaborative Protein Technology Resource - Nano-Scale Protein Analysis Section
Mouse Cancer Genetics ProgramKeller, JonathanZIA BC 010001Molecular-Cellular Regulation of Hematopoietic Stem Cells
Laboratory of Genitourinary Cancer PathogenesisKelly Siebenlist, KathleenZIA BC 010802Tumor stem cells and metastatic outcomes in mouse models of prostate cancer
Laboratory of Genitourinary Cancer PathogenesisKelly Siebenlist, KathleenZIA BC 011053TMPRSS2-ERG chromosomal translocations and prostate cancer
Laboratory of Genitourinary Cancer PathogenesisKelly Siebenlist, KathleenZIA BC 011782Mechanisms of pathogenesis in patient derived organoid models of prostate cancer
Laboratory of Genitourinary Cancer PathogenesisKelly Siebenlist, KathleenZIA BC 011919Identifying genetic vulnerabilities in neuroendocrine prostate cancer
Laboratory of Biochemistry and Molecular BiologyKelly, AlexanderZIA BC 011491Role of kinetochore proteins in chromosome segregation
Laboratory of Cell and Developmental SignalingKettenhofen, ChristineZIC BC 011956Zebrafish core
Basic Research LaboratoryKewalRamani, VineetZIA BC 010487The role of CPSF6 in HIV-1 infection
Basic Research LaboratoryKewalRamani, VineetZIA BC 010488HIV-1 passage through the nuclear pore complex
Basic Research LaboratoryKewalRamani, VineetZIA BC 011461SARS-CoV-2 and HIV-1 Interactions with C-Type Lectins
Genetics BranchKhan, JavedZIA BC 010806Developing Novel Therapies for Neuroblastoma and Rhabdomyosarcoma
Genetics BranchKhan, JavedZIA BC 010998Novel Mutations and Therapy Resistance Mechanisms in Pediatric Cancers
Genetics BranchKhan, JavedZIA BC 010999Targeting FGFR4, RAS, and PAX3-FOXO1 gene in Rhabdomyosarcoma
Genetics BranchKhan, JavedZIA BC 011002Bioinformatics: Systems Biology of Cancers
Genetics BranchKhan, JavedZIA SC 010366Predicting Response & Prognosis in Pediatric Cancers
Laboratory of Molecular BiologyKhare, AnupamaZIA BC 011819Mechanisms of multi-species bacterial interactions
Laboratory of Molecular BiologyKhare, AnupamaZIA BC 011821Evolution of antibiotic resistance
Laboratory of MetabolismKimura, ShiokoZIA BC 005522Thyroid regeneration and carcinogenesis
Laboratory of MetabolismKimura, ShiokoZIA BC 010449Role of Novel Cytokine Secretoglobin (SCGB) 3A2 in Lung
Laboratory of PathologyKleiner, DavidZIC BC 010685Postmortem Pathology
Molecular Imaging BranchKobayashi, HisatakaZIA BC 011512Activatable molecular cancer imaging probe
Molecular Imaging BranchKobayashi, HisatakaZIA BC 011513Cancer-cell specific therapy: photo-immunotherapy
Surgery BranchKochenderfer, JamesZIA BC 011415Allogeneic T cells Transduced with an Anti-CD19 Chimeric Antigen Receptor
Surgery BranchKochenderfer, JamesZIA BC 011417Improved Chimeric Antigen Receptor Therapies B-cell Malignancies
Surgery BranchKochenderfer, JamesZIA BC 011439Development of Chimeric Antigen Receptors Targeting Multiple Myeloma
Surgery BranchKochenderfer, JamesZIA BC 011660Development of fully-human anti-CD30 chimeric antigen receptors
Office of the DirectorKong, HeidiZIA BC 010914Gene Expression Profiling and Clinical Characterization of Phototoxicity
Office of the DirectorKong, HeidiZIA BC 010938Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis Patients
Office of the DirectorKong, HeidiZIA BC 010940Cutaneous Adverse Drug Reactions
Office of the DirectorKong, HeidiZIA BC 011558Effects of systemic and topical perturbations on human microbes
Office of the DirectorKong, HeidiZIA BC 011881Investigating the microbiome in persons living with HIV
Laboratory of Cancer Biology and GeneticsKraemer, KennethZIA BC 004517DNA Repair in Human Cancer-Prone Genetic Diseases
Laboratory of Molecular BiologyKreitman, RobertZIA BC 010301Development of Recombinant Toxins to Treat Hematologic Malignancies
Laboratory of Molecular BiologyKreitman, RobertZIA BC 011952Patterns of immune response in COVID-19 patients
HIV and AIDS Malignancy BranchKrug, LaurieZIA BC 011953Investigation of viral and host determinants of gammaherpesvirus pathogenesis
HIV and AIDS Malignancy BranchKrug, LaurieZIA BC 012014Novel interventions for gammaherpesvirus infection and AIDS-Related Malignancies
Laboratory of Cancer Biology and GeneticsKruhlak, MichaelZIC BC 010858CCR Microscopy Core
Laboratory of Genitourinary Cancer PathogenesisLake, RossZIC BC 010947Laboratory of Genitourinary Cancer Pathogenesis Microscopy Core Facility
Genetics BranchLal, AshishZIA BC 011646Role of long non-coding RNAs and RNA-binding proteins in p53 signaling
Neuro-Oncology BranchLarion, MioaraZIA BC 011707The effect of therapeutics on mutated IDH1 cell lines and mice tumor models
Neuro-Oncology BranchLarion, MioaraZIA BC 011708Targeted and untargeted metabolomics in IDH1 mutated xenografts in mice
Neuro-Oncology BranchLarion, MioaraZIA BC 011709Metabolite profiling of patients blood, urine, cerebrospinal fluid and tissue
Neuro-Oncology BranchLarion, MioaraZIA BC 011710In vivo and in vitro metabolic flux analysis in preclinical mouse models
Neuro-Oncology BranchLarion, MioaraZIA BC 011711Develop RAMAN imaging to visualize metabolism in cell lines and tissue
Developmental Therapeutics BranchLarionov, VladimirZIA BC 010413Human Artificial Chromosomes for Cancer Research and Functional Genomics
Laboratory of Receptor Biology and Gene ExpressionLarson, DanielZIA BC 011383Transcription and Splicing Dynamics in Single Cells
Genitourinary Malignancies BranchLassoued, WiemZIC BC 012029Tumor Immune MicroEnvironment Facility
Laboratory of Cell BiologyLavi, OritZIA BC 011758Predicting the probabilistic complex invasive map of GBM cells
Laboratory of Cell BiologyLavi, OritZIA BC 011926Predicting the adaptation processes of GBM cells due to spatiotemporal stimuli
Experimental Immunology BranchLazarevic, VanjaZIA BC 011431Role of T-bet in the pathogenesis of experimental autoimmune encephalomyelitis
Experimental Immunology BranchLazarevic, VanjaZIA BC 011765Transcriptional regulation of inflammatory and autoimmune responses
Laboratory of Genome IntegrityLazzerini Denchi, ErosZIA BC 011815Investigate the mechanism of action of the novel telomere length regulator TZAP
Laboratory of Genome IntegrityLazzerini Denchi, ErosZIA BC 011816Determine how telomere dysfunction impacts neuronal function
Laboratory of Genome IntegrityLazzerini Denchi, ErosZIA BC 012015mechanism of end protection in stem cells
Basic Research LaboratoryLe Grice, StuartZIA BC 010493Nucleic Acid Footprinting and development of small molecule antagonists
Basic Research LaboratoryLe Grice, StuartZIA BC 010494Small molecule targeting viral nucleotidyltransferases
Basic Research LaboratoryLe Grice, StuartZIA BC 011824Structural studies with regulatory RNAs
Center for Structural BiologyLea, SusanZIA BC 012043Structural biology of host-pathogen interactions
Laboratory of Cellular and Molecular BiologyLebensohn, AndresZIA BC 011901New regulatory mechanisms of WNT signaling in development, stem cells and cancer
Molecular Imaging BranchLeblanc, AmyZIA BC 011692Comparative Oncology Program Laboratory
Molecular Imaging BranchLeblanc, AmyZIA BC 011696Comparative Brain Tumor Consortium
Molecular Imaging BranchLeblanc, AmyZIG BC 011689Comparative Oncology Trials Consortium
Women's Malignancies BranchLee, Jung-MinZIA BC 011525Leveraging DNA damage repair pathways as therapeutic targets in womens cancers
Laboratory of MetabolismLee, KyungZIA BC 010681Development of inhibitors targeting Plk1 polo-box domain
Laboratory of MetabolismLee, KyungZIA BC 011518Molecular basis of centriole duplication
Laboratory of MetabolismLee, KyungZIA BC 012024Unraveling the molecular link between HIV/AIDS and cancer
Laboratory of Cancer Biology and GeneticsLee, MaxwellZIH BC 011703Integrated analyses of genetics, epigenetics, and gene expression
Laboratory of PathologyLevens, DavidZIA BC 011011The genome-wide function of supercoiling and alternative DNA conformations
Laboratory of PathologyLevens, DavidZIA BC 011465c-Myc Function
Laboratory of PathologyLevens, DavidZIA SC 009144Mechanisms of transcription factor integration at the c-myc promoter
Office of the DirectorLevine, JasonZIH BC 011235Support of NCI CCR Clinical Research and Bioinformatics
Cancer and Developmental Biology LaboratoryLewandoski, MarkZIA BC 010338The Role of Fgf Signaling in Vertebrate Development
Cancer and Developmental Biology LaboratoryLewandoski, MarkZIA BC 010518Role of BMP and FGF signaling during limb development
Cancer and Developmental Biology LaboratoryLewandoski, MarkZIA BC 011321Identification and characterization of FGF target genes
Laboratory of Biochemistry and Molecular BiologyLichten, MichaelZIA BC 005268Mechanism of Meiotic Recombination
Molecular Imaging BranchLin, FrankZIA BC 011789Phase 2 study of Lu-177-DOTATATE in inoperable paraganglioma - pheochromocytoa
Molecular Imaging BranchLin, FrankZIA BC 011825Th227-mesothelin and Zr89-mesothelin antibody conjugate in mesothelin tumors
Molecular Imaging BranchLin, FrankZIA BC 011826Protection of Salivary Gland in PSMA-targeted radioligand therapy
Molecular Imaging BranchLin, FrankZIA BC 011827Phase 1-2 study of Lu177-DOTATATE and olaparib in neuroendocrine tumors
Molecular Imaging BranchLin, FrankZIA BC 011895Improving PSMA-based radioligand therapy via combination radioligand therapy
Urologic Oncology BranchLinehan, W. MarstonZIA BC 011028Clinical Studies of the Molecular Genetic Basis of Kidney Cancer
Urologic Oncology BranchLinehan, W. MarstonZIA BC 011038Molecular Therapeutics of Kidney Cancer: VHL Gene and Fumarate Hydratase Gene
Urologic Oncology BranchLinehan, W. MarstonZIA BC 011043Molecular Therapeutics of Kidney Cancer: MET Gene and BHD Gene
Urologic Oncology BranchLinehan, W. MarstonZID BC 011089Clinical Nursing and Data Management Core
Urologic Oncology BranchLinehan, W. MarstonZID BC 011092Urologic Oncology Branch Consult Core
Women's Malignancies BranchLipkowitz, StanleyZIA BC 010977Cbl Proteins as Regulators of Tyrosine Kinase Signaling
Women's Malignancies BranchLipkowitz, StanleyZIA BC 011650Genomic characterization of breast cancer in high risk subsets of breast cancer
Women's Malignancies BranchLipkowitz, StanleyZIA SC 007263Activating Cell Death Pathways in Breast Cancer Cells
Laboratory of Immune Cell BiologyLiu, Zheng-GangZIA BC 010783Inflammation, Macrophage Differentiation, and Cancer
Laboratory of Immune Cell BiologyLiu, Zheng-GangZIA SC 010376TNF Signaling, Cell Death and Cancer
Laboratory of Genome IntegrityLivak, FerencZIC BC 011428CCR, LGI, Flow Cytometry Core
Laboratory of Protein Dynamics and SignalingLoncarek, JadrankaZIA BC 011459Control of centrosome biogenesis
Laboratory of Cellular OncologyLowy, DouglasZIA BC 008905Tumor gene expression in vitro and in vivo
Laboratory of Cellular OncologyLowy, DouglasZIA BC 010579Papillomavirus Virion Proteins and Vaccines
Laboratory of Cancer Biology and GeneticsLuo, JiZIA BC 011303Role of the protein SUMOylation pathway in Ras-driven oncogenesis
Laboratory of Cancer Biology and GeneticsLuo, JiZIA BC 011304Methods for mammalian genetic analysis
Laboratory of Cancer Biology and GeneticsLuo, JiZIA BC 011437Combinatorial genetic analysis using validated siRNA libraries
Laboratory of Cancer Biology and GeneticsLuo, JiZIA BC 011438Genetic screens for target discovery in cancer
Laboratory of Cancer Biology and GeneticsLuo, JiZIA BC 011732Discovery of combination therapy for KRAS mutant cancer
Laboratory of Cancer Biology and GeneticsLuo, JiZIA BC 011733Mechanism of anchorage independent growth driven by the KRAS oncogene
Cancer and Developmental Biology LaboratoryMackem, SusanZIA BC 011118Role of Shh in developmental patterning and growth of digit skeleton
Cancer and Developmental Biology LaboratoryMackem, SusanZIA BC 011119Hoxd and Gli3-Hoxd interaction roles in Hedgehog regulated digit morphogenesis
Cancer and Developmental Biology LaboratoryMackem, SusanZIA BC 011120Genome-wide target analysis of Shh-activated transcription network in limb bud
Cancer and Developmental Biology LaboratoryMackem, SusanZIA BC 011319Role of FIR in limb morphogenesis
Cancer and Developmental Biology LaboratoryMackem, SusanZIA BC 011835Minimal Myc functional threshold for tumorigenesis
Genitourinary Malignancies BranchMadan, RaviZIA BC 011896Evaluation of immunotherapy-novel treatments in biochemically recurrent prostate
Genitourinary Malignancies BranchMadan, RaviZIA BC 011897Evaluation of Immune-based Combinations in Metastatic Prostate Cancer
Genitourinary Malignancies BranchMadan, RaviZIA BC 011898Development of Immunotherapy for Medullary Thyroid Cancer
Genitourinary Malignancies BranchMadan, RaviZIA BC 012060Novel Anti-androgen strategies in Prostate Cancer
HIV DRP Host-Virus Interaction BranchMaldarelli, FrankZIA BC 010819HIV-1 Genetic Variation in Infected Individuals
HIV DRP Host-Virus Interaction BranchMaldarelli, FrankZIA BC 011464Clinical Interventional Studies of HIV Reservoirs
HIV DRP Host-Virus Interaction BranchMaldarelli, FrankZIA BC 011466HIV Persistence During Suppressive Antiretroviral Therapy
Basic Research LaboratoryMatsuo, HiroshiZIC BC 011849Structural studies of biomolecules related to cancer and HIV-AIDS
Experimental Immunology BranchMayer, ChristianZIA BC 011975The role of apoptosis in B lymphocyte biology
Experimental Immunology BranchMayer, ChristianZIA BC 012038Antibody responses to viruses
Pediatric Oncology BranchMcEachron, TroyZIA BC 012056Identification of immune evasion mechanisms in the osteosarcoma microenvironment
Vaccine BranchMcKinnon, KatherineZIC BC 010936CCR Vaccine Branch FACS Core
Laboratory of Cancer ImmunometabolismMcVicar, DanielZIA BC 010300Immunometabolism in Cancer and Inflammation
Chemical Biology LaboratoryMeier, JordanZIA BC 011488Chemical Biology Platforms to Define the Metabolism-Epigenetics Interface
Genetics BranchMeltzer, PaulZIA BC 010759Functional Genomics of Sarcoma
Genetics BranchMeltzer, PaulZIA BC 011091Cancer Genomics Technology Development
Genetics BranchMeltzer, PaulZIA BC 011328Characterization of the Osteosarcoma Genome
Laboratory of PathologyMerino, MariaZIA BC 010696Study of Hereditary Renal and Other Familial Syndromes
Laboratory of PathologyMerino, MariaZIA BC 011405microRNA Profiling in the Spectrum of Kidney Tumors
Laboratory of PathologyMerino, MariaZIA BC 011406miRNA profiling of prostate cancer in young and older male patients
Laboratory of PathologyMerino, MariaZIA BC 012016Immunotherapy of kidney cancer. Where do the T lymphocytes go in kidney cancer?
Laboratory of PathologyMerino, MariaZIE SC 000853Translational Surgical Pathology
Laboratory of Cancer Biology and GeneticsMerlino, GlennZIA BC 008756Genetically Engineered Mouse Models to Study Melanoma Genesis and Progression
Laboratory of Cancer Biology and GeneticsMerlino, GlennZIA BC 011167Preclinical Mouse Models for Studying Immune Checkpoint Inhibitor Response
Laboratory of PathologyMiettinen, MarkkuZIA BC 011427Immunohistochemical and genomic analysis of tumors
Laboratory of PathologyMiettinen, MarkkuZID BC 011291General Surgical Pathology
Laboratory of Cellular and Molecular BiologyMili, StavroulaZIA BC 011501Regulation and functional effects of localized RNAs
Radiation Oncology BranchMiller, RobertZIA BC 010516Gated Optical Detectors-Dose Guided Radiotherapy
Radiation Oncology BranchMiller, RobertZIA SC 006330Radiation Field Modeling and Computerized Treatment Planning
Radiation Oncology BranchMiller, RobertZID SC 006329Clinical Radiation Physics Service
Laboratory of Receptor Biology and Gene ExpressionMisteli, TomZIA BC 010309Nuclear Architecture and Disease
Office of the DirectorMisteli, TomZIC BC 011021Basic Research Support for the CCR
Office of the DirectorMisteli, TomZIC BC 011933Office of Translational Resources
Office of the DirectorMisteli, TomZID BC 011022Clinical Research Support for the CCR
Office of the DirectorMisteli, TomZIJ BC 011133CCR Office of Training and Education
Radiation Biology BranchMitchell, JamesZIA BC 010946Protection against Radiation-Induced Carcinogenesis
Radiation Biology BranchMitchell, JamesZIA SC 006321Modulation of Therapeutic Response
Radiation Biology BranchMitchell, JamesZIA SC 006387Nitroxides as Protectors Against Oxidative Stress
HIV and AIDS Malignancy BranchMitsuya, HiroakiZIA BC 011486Development of Novel Agents Active against Hepatitis B Virus
HIV and AIDS Malignancy BranchMitsuya, HiroakiZIA BC 012018Development of therapeutics for SARS-CoV-2 infection
HIV and AIDS Malignancy BranchMitsuya, HiroakiZIA SC 006738Development of Antiviral Therapy of HIV-1 Infection
Laboratory of Cancer Biology and GeneticsMock, BeverlyZIA BC 010008The Genetics of Susceptibility to Mouse Plasma Cell Tumors
Laboratory of Cancer Biology and GeneticsMock, BeverlyZIA BC 011064A Modifier of Plasmacytoma Susceptibility Maps to Mouse Chr 1
Laboratory of Cancer Biology and GeneticsMock, BeverlyZIA BC 011065Preclinical Testing of Drug Combinations (HDAC, mTOR, CDK and MYC Inhibitors)
Laboratory of Cell and Developmental SignalingMorrison, DeborahZIA BC 010329Regulation of Ras-Dependent Signal Transduction Pathways
Laboratory of Cell and Developmental SignalingMorrison, DeborahZIA BC 011107Role of Protein Scaffolds in RTK-Ras-dependent Signal Transduction
Mouse Cancer Genetics ProgramMuegge, KathrinZIA BC 010014Epigenetic control during embryogenesis
Lymphoid Malignancies BranchMuppidi, JaganZIA BC 011772The role of Galpha13 signaling in suppression of lymphoma
Laboratory of Cancer Biology and GeneticsMurgai, MeeraZIA BC 012006Perivascular plasticity in metastatic microenvironments
Office of the DirectorNagao, KeisukeZIA BC 011561Exploring mechanisms that govern immune homeostasis in skin
Developmental Therapeutics BranchNeckers, JaneZIC SC 006743Signal Transduction Events and the Regulation of Cell Growth
Urologic Oncology BranchNeckers, LeonardZIA BC 010683Role of FH loss in development of HLRCC heriditary kidney cancer
Urologic Oncology BranchNeckers, LeonardZIA BC 011032Post-translational modifications of Hsp90
Urologic Oncology BranchNeckers, LeonardZIA SC 010074HSP90 Chaperone Proteins and Interactors in Cellular Signal Transduction
Pediatric Oncology BranchNellan, AnandaniZIA BC 012059Study of CAR T cells and mechanisms of resistance in pediatric brain tumors
Chemical Biology LaboratoryNicklaus, MarcZIA BC 010524HIV Integrase Modeling and Computer-Aided Inhibitor and Microbicide Development
Chemical Biology LaboratoryNicklaus, MarcZIA BC 010832Fundamentals of Ligand-Protein Interactions
Chemical Biology LaboratoryNicklaus, MarcZIA BC 011666Synthetically Accessible Virtual Inventory (SAVI)
Chemical Biology LaboratoryNicklaus, MarcZIA BC 011785Better Understanding and Handling of Tautomerism
Chemical Biology LaboratoryNicklaus, MarcZIC BC 010517Large Databases of Small Molecules - Drug Development Tool and Public Resource
Chemical Biology LaboratoryNicklaus, MarcZIC BC 010639In Silico Screening for Cancer Targets
Surgical Oncology ProgramNilubol, NarisZIA BC 011286Therapeutic targets and novel anticancer agents for endocrine cancers
Laboratory of Genome IntegrityNussenzweig, AndreZIA BC 010283DNA repair
Laboratory of Genome IntegrityNussenzweig, AndreZIA BC 010959Relationship between DNA damage detection and signaling
Laboratory of Cancer ImmunometabolismNussinov, RuthZIA BC 010440Protein Structure, Stability, and Amyloid Formation
Laboratory of Cancer ImmunometabolismNussinov, RuthZIA BC 010441Biomolecular Recognition and Binding Mechanisms
Laboratory of Cancer ImmunometabolismNussinov, RuthZIA BC 010442Method Development: Efficient Computer Vision Based Algorithms
Laboratory of Integrative Cancer ImmunologyO'Huigin, ColmZIC BC 011237LICI Microbiome and Genetics Core
Molecular Targets ProgramO'Keefe, BarryZIA BC 011471Cell-free assay technologies for the identification of active compounds
Molecular Targets ProgramO'Keefe, BarryZIA BC 011472Isolation of bioactive proteins from natural product extracts
Office of the DirectorO'Keefe, BarryZIA BC 011854NCI Program for Natural Products Discovery - Cures
Molecular Targets ProgramO'Keefe, BarryZIA BC 011904Assay development and screening for molecular targets and discovery
Laboratory of Receptor Biology and Gene ExpressionOberdoerffer, ShaliniZIA BC 011293Cytidine modifications in mRNA processing and function
Laboratory of Cancer ImmunometabolismOppenheim, JoostZIA BC 009369Studies of Receptor Interactions and Effects of Alarmins
Laboratory of Cancer ImmunometabolismOppenheim, JoostZIA BC 010707Role of T Regulatory Cell Suppression in Autoimmunity and Cancer
Immune Deficiency and Cellular Therapy ProgramPai, Sung-YunZIA BC 012039Pathobiology and treatment of patients with severe combined immunodeficiency
Immune Deficiency and Cellular Therapy ProgramPai, Sung-YunZIA BC 012040Pathobiology and treatment of patients with inborn errors of immunity
Immune Deficiency and Cellular Therapy ProgramPai, Sung-YunZID BC 012026ID-CTP Clinical Core
Laboratory of Tumor Immunology and BiologyPalena, ClaudiaZIC BC 010937Novel Targets for Immunotherapy
Experimental Immunology BranchPark, Jung-HyunZIA BC 011214Post-Transcriptional Regulation of Interleukin-7 Receptor Expression
Experimental Immunology BranchPark, Jung-HyunZIA BC 011215Immune Regulatory Roles of Suppressor Of Cytokine Signaling (SOCS) Molecules
Surgery BranchParkhurst, MariaZIC BC 011030The Antigen Targeting Core
Laboratory of Molecular BiologyPastan, IraZIA BC 008753Immunotoxin Therapy of Solid and Hematopoietic Tumors: Preclinical Studies
Laboratory of Molecular BiologyPastan, IraZIA BC 010020Clinical Trials with Immunotoxins
Laboratory of Molecular BiologyPastan, IraZIA BC 010298Growth Regulation Section
HIV DRP Retroviral Replication LaboratoryPathak, VinayZIA BC 010595Structure and Function of Vif and APOBEC3 (A3) Proteins
HIV DRP Retroviral Replication LaboratoryPathak, VinayZIA BC 011436Viral Replication and Interactions with Host Factors
Vaccine BranchPavlakis, GeorgeZIA BC 010749Immunotherapeutic Approaches for AIDS
Vaccine BranchPavlakis, GeorgeZIA BC 010750Heterodimeric IL-15 in Cancer Immunotherapy
Vaccine BranchPavlakis, GeorgeZIA BC 011939COVID-19 vaccine development
Immune Deficiency and Cellular Therapy ProgramPavletic, StevenZIA BC 011743NIH Chronic GVHD Study Group
Immune Deficiency and Cellular Therapy ProgramPavletic, StevenZIA BC 012017NIH Myeloid Malignancy Program
Laboratory of Receptor Biology and Gene ExpressionPegoraro, GianlucaZIC BC 011567HiTIF Microscopy Core Facility
Urologic Oncology BranchPinto, PeterZIA BC 011081Prostate Section
Urologic Oncology BranchPinto, PeterZIE BC 011023Clinical Fellowship Training Program
Developmental Therapeutics BranchPommier, YvesZIA BC 006150DNA Repair, Cell Cycle Checkpoints and Apoptosis as Targets for Anticancer Drugs
Developmental Therapeutics BranchPommier, YvesZIA BC 006161DNA Topoisomerases as nuclear and mitochondrial targets of Anticancer Drugs
Developmental Therapeutics BranchPommier, YvesZIA BC 011746Development Therapeutics Branch Clinical Trials
Developmental Therapeutics BranchPommier, YvesZIA BC 011948TOP3B as host factor and drug target
Thoracic and GI Malignancies BranchPorat-Shliom, NatalieZIA BC 011828Mitochondrial metabolism in normal and transformed cells
Cancer Data Science LaboratoryRajagopal, PadmaZIA BC 012057Identifying germline-somatic and synthetic lethal targets in hereditary cancers
Cancer Data Science LaboratoryRajagopal, PadmaZIA BC 012058Identifying synthetic lethal targets in metastatic triple negative breast cancer
Thoracic and GI Malignancies BranchRajan, ArunZIA BC 011900Pilot Study of Avelumab in Thymic Epithelial Tumors
Thoracic and GI Malignancies BranchRajan, ArunZIA BC 011902Anetumab in Thymic Carcinoma
Thoracic and GI Malignancies BranchRajan, ArunZIA BC 011905Anti-PD-L1-TGFb antibody (M7824) in advanced non-small cell lung cancer
Thoracic and GI Malignancies BranchRajan, ArunZIA BC 011906CV301 and Anti-PD-1 Therapy in Non-Small Cell Lung Cancer
Thoracic and GI Malignancies BranchRajan, ArunZIA BC 011907Durvalumab in Combination with Olaparib in Non-Small Cell Lung Cancer
Thoracic and GI Malignancies BranchRajan, ArunZIA BC 012001Phase II Trial of Bintrafusp Alfa in Subjects with Thymoma and Thymic Carcinoma
Laboratory of Molecular BiologyRamamurthi, KumaranZIA BC 011211Subcellular protein localization in B. subtilis
HIV and AIDS Malignancy BranchRamaswami, RamyaZIA BC 011954Targeted therapies for Kaposi sarcoma and KSHV-multicentric Castleman disease
Laboratory of Cellular and Molecular BiologyRandazzo, PaulZIA BC 007365Regulation of ADP-ribosylation factor
Pediatric Oncology BranchReilly, KarlyneZIA BC 011754Molecular, Cellular and Genetic Analyses of Malignancies Associated with NF1
HIV DRP Retroviral Replication LaboratoryRein, AlanZIA BC 010511Retrovirus Assembly and Maturation
HIV DRP Retroviral Replication LaboratoryRein, AlanZIA BC 010512Interactions of Retroviral Proteins with Nucleic Acids
HIV DRP Retroviral Replication LaboratoryRein, AlanZIA BC 011325Retrovirus Biology
HIV DRP Retroviral Replication LaboratoryRein, AlanZIA BC 011991Actions of Restriction Factors on Coronaviruses
Developmental Therapeutics BranchReinhold, WilliamZIC BC 011475Genomics and Bioinformatics Group web site development and maintenance
Developmental Therapeutics BranchReinhold, WilliamZIC BC 011497RNA data development of of cancer cell lines and patients.
Developmental Therapeutics BranchReinhold, WilliamZIC BC 011509Comparison of molecular factors to drug activities
Developmental Therapeutics BranchReinhold, WilliamZIC BC 011820DNA data development for cancer cell lines and patients
Genetics BranchRied, ThomasZIA BC 010833Colorectal Cancer Transcriptome: Effects of Genomic Instability and Aneuploidy
Genetics BranchRied, ThomasZIA BC 010834Identifying Diagnostic Markers for Cervical, Breast, and Prostate Cancer
Genetics BranchRied, ThomasZIA BC 010837Disease prognostication and treatment response in rectal cancer patients
Genetics BranchRied, ThomasZIA BC 012061Prediction of Therapy Response in Colorectal Cancer
Surgery BranchRobbins, PaulZIC BC 010948DNA Sequencing and FACS Core Facilities
Laboratory of PathologyRoberts, DavidZIA SC 009172Cellular Interactions with Thrombospondin
Laboratory of PathologyRoberts, DavidZIA SC 009174Roles of CD47 Signaling in Tumor Immunology
Experimental Immunology BranchRoche, PaulZIA BC 009404Regulation of MHC Class II Trafficking in Antigen Presenting Cells
Experimental Immunology BranchRoche, PaulZIA BC 011035Regulation of Exocytosis from Immune Cells
Experimental Immunology BranchRoche, PaulZIA BC 011687Dysregulation of Antigen Presenting Cell Function in Cancer
Developmental Therapeutics BranchRoper, NitinZIA BC 011989Epigenetic and immunologic aspects of neuroendocrine cancers
Developmental Therapeutics BranchRoper, NitinZIA BC 012053Developing ACC patient-derived organoids to identify therapeutic vulnerabilities
Lymphoid Malignancies BranchRoschewski, MarkZIA BC 011914Molecular Biology of Lymphoma
Lymphoid Malignancies BranchRoschewski, MarkZIA BC 011916Pathway inhibitors in Lymphomas
Surgery BranchRosenberg, StevenZIA BC 010984Adoptive Cell Transfer Immunotherapy of Cancer
Surgery BranchRosenberg, StevenZIA BC 010985Gene therapy of cancer
OCD-OD AdminRoyce, CherylZID BC 010882Center for Cancer Research Clinical Trials Support
OCD-OD AdminRoyce, CherylZID BC 010987Center for Cancer Research Patient Travel
OCD-OD AdminRoyce, CherylZID BC 011716CCR Research Nursing
Pediatric Oncology BranchRudloff, UdoZIA BC 011267Preclinical drug development in pancreatic cancer
Laboratory of Genome IntegrityRuiz Macias, SergioZIA BC 011808Role of ETS-Transcription Factors in Regulating Cell Fate
Laboratory of Genome IntegrityRuiz Macias, SergioZIA BC 011809Identification of molecular pathways regulating quiescence in pluripotent cells
Laboratory of Genome IntegrityRuiz Macias, SergioZIA BC 011813Molecular Determinants of Totipotency
Cancer Data Science LaboratoryRuppin, EytanZIA BC 011802Discovery of genetic interactions in cancer
Cancer Data Science LaboratoryRuppin, EytanZIA BC 011803Cancer immunotherapy
Cancer Data Science LaboratoryRuppin, EytanZIA BC 012000Discovering Affective Drug Combinations for Treating Covid-19
Laboratory of Human CarcinogenesisRyan, BridZIA BC 011554Lung Cancer Health Disparities
Laboratory of Human CarcinogenesisRyan, BridZIA BC 011555Gene-Environment Interactions in Lung Cancer
Surgical Oncology ProgramSadowski, SamiraZIA BC 011899Targeted Therapy in Neuroendocrine Cancer
Cancer Data Science LaboratorySahinalp, Suleyman CenkZIA BC 011987Tumor evolution and intratumor heterogeneity
Cancer Data Science LaboratorySahinalp, Suleyman CenkZIA BC 011988Privacy Preserving Genome Analysis
Thoracic and GI Malignancies BranchSaloura, VassilikiZIA BC 011831The Role of Protein Methylation in Squamous Cell Carcinoma of the Head and Neck
Thoracic and GI Malignancies BranchSaloura, VassilikiZIA BC 011859IMRRT for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma
Laboratory of Cellular and Molecular BiologySamelson, LawrenceZIA BC 010304Biochemical Basis of T Cell Activation
Laboratory of Cellular OncologySchiller, JohnZIA BC 009052Understanding Papillomavirus Virion Proteins and Vaccines
Laboratory of Tumor Immunology and BiologySchlom, JeffreyZIA BC 010425Strategies for Cancer Immunotherapy Clinical Trials
Laboratory of Tumor Immunology and BiologySchlom, JeffreyZIA BC 010598Human Immune Responses to Tumor Antigens for Cancer Immunotherapy
Laboratory of Tumor Immunology and BiologySchlom, JeffreyZIA BC 010944Strategies for Cancer Immunotherapy Development: Preclinical Studies
Chemical Biology LaboratorySchneekloth, JohnZIA BC 011585Identification of Nucleic Acid Binding Small Molecules
Chemical Biology LaboratorySchneekloth, JohnZIA BC 011970Targeting Functional RNA Elements in the SARS-CoV-2 Genome
Chemical Biology LaboratorySchneider, JoelZIA BC 011313Design and Utility of Novel Proteinaceous Biomaterials
Chemical Biology LaboratorySchneider, JoelZIA BC 011314Development of antibacterial agents and materials
Chemical Biology LaboratorySchneider, JoelZIC BC 011515Chemical Synthesis Group
Chemical Biology LaboratorySchneider, JoelZIC BC 011958Medicinal Chemistry Core
Chemical Biology LaboratorySchnermann, MartinZIA BC 011506New Synthetic Approaches to Small Molecules for Imaging
Chemical Biology LaboratorySchnermann, MartinZIA BC 011564Near-IR Photorelease Chemistry: Discovery and Applications
Chemical Biology LaboratorySchroeder, ChristinaZIA BC 011960Discovery and characterisation of recifin
Chemical Biology LaboratorySchroeder, ChristinaZIA BC 011998Synthesis and Development of Trefoil Factor Peptides
Chemical Biology LaboratorySchroeder, ChristinaZIA BC 012002Development of imaging probes for surgery
Chemical Biology LaboratorySchroeder, ChristinaZIA BC 012003Discovery and development of voltage-gated sodium channel inhibitors
Chemical Biology LaboratorySchroeder, ChristinaZIA BC 012004Discovery of bioactive peptides targeting ion channels upregulated in cancer
Thoracic Surgery BranchSchrump, DavidZIA BC 011115Epigenetic Mechanisms of Gene Expression in Thoracic Malignancies
Thoracic Surgery BranchSchrump, DavidZIA BC 011418Modulating Cancer Stem Cell Signaling in Thoracic Malignancies
Thoracic Surgery BranchSchrump, DavidZIA SC 010093Epigenetic Therapy for Thoracic Malignancies
Thoracic Surgery BranchSchrump, DavidZID BC 011911Thoracic Surgery Consultative Services
Pediatric Oncology BranchShah, NiraliZIA BC 011823Development of Novel Therapies for Acute Lymphoblastic Leukemia
Pediatric Oncology BranchShah, NiraliZIA BC 011927Clinical Development of Immunotherapies for Rare Hematologic Maligancies
RNA Biology LaboratoryShapiro, BruceZIA BC 008382Computational Approaches for RNA Structure and Function Determination
RNA Biology LaboratoryShapiro, BruceZIA BC 011061Computational and Experimental RNA Nanobiology
Mouse Cancer Genetics ProgramSharan, ShyamZIA BC 010387Functional Analysis of Breast Cancer Susceptibility Genes in Mice
Mouse Cancer Genetics ProgramSharan, ShyamZIA BC 011181Functional Analysis of Human Breast Cancer Susceptibility Gene Variants
Mouse Cancer Genetics ProgramSharan, ShyamZIA BC 011311Identification of genetic interactors of Brca2
Center for Advanced Preclinical ResearchSharan, ShyamZIA BC 011736Preclinical Development of Therapeutics in Murine Models of Lung Cancer
Center for Advanced Preclinical ResearchSharan, ShyamZIA BC 011737Therapeutic evaluation in ovarian and breast cancer GEM-GDA models
Center for Advanced Preclinical ResearchSharan, ShyamZIA BC 011738Preclinical GEM and GDA Models of Primary and Metastatic Melanoma
Center for Advanced Preclinical ResearchSharan, ShyamZIA BC 011739Development and Preclinical Applications of Pancreatic Adenocarcinoma Models
Center for Advanced Preclinical ResearchSharan, ShyamZIA BC 011848Preclinical Modelling and Therapeutic Development for Other Cancer Indications
Center for Advanced Preclinical ResearchSharan, ShyamZIG BC 011735Development of Novel Informative Preclinical Animal Models - CAPR Infrastructure
Experimental Immunology BranchSharrow, SusanZIC BC 009255Application of Flow Cytometry to Cell Biology
Pediatric Oncology BranchShern, JohnZIA BC 011722Genomic characterization and development of therapies for pediatric sarcoma
Pediatric Oncology BranchShern, JohnZIA BC 011734Genomic dissection of tumor heterogeneity and progression
OCD-OD AdminShorer, ShyZID BC 011875Office of Sponsor and Regulatory Oversight
Laboratory of Cancer Biology and GeneticsSimpson, R. MarkZIC BC 010953Computational Molecular Pathology Research for Cancer Diagnostics and Biomarkers
Laboratory of Cancer Biology and GeneticsSimpson, R. MarkZIG BC 010931Comparative Biomedical Scientist Training Program
Experimental Immunology BranchSinger, AlfredZIA BC 009273T Cell Differentiation and Repertoire Selection
Experimental Immunology BranchSinger, AlfredZIA BC 011106Specification of T cell function during development
Experimental Immunology BranchSinger, AlfredZIA BC 011111Cytokine signaling in developing thymocytes and T cells
Experimental Immunology BranchSinger, AlfredZIA BC 011112Development and function of regulatory T cells
Experimental Immunology BranchSinger, AlfredZIA BC 011113T cell survival
Experimental Immunology BranchSinger, AlfredZIA BC 011114Role of microRNAs in T cell development
Experimental Immunology BranchSinger, AlfredZIA BC 011116MHC-independent T cells
Experimental Immunology BranchSinger, AlfredZIA BC 011117T cell receptor regulation of cytokine signaling
Experimental Immunology BranchSinger, DinahZIA BC 011381Brd4 is an atypical kinase that regulates transcription
Experimental Immunology BranchSinger, DinahZIA BC 011688In vivo function of BRD4
Experimental Immunology BranchSinger, DinahZIA BC 011882Interactions Between MYC and BRD4 Result in Their Reciprocal Regulation
Experimental Immunology BranchSinger, DinahZIA BC 011883BRD4 Contributes to the Regulation of Alternative Splicing
Experimental Immunology BranchSinger, DinahZIA BC 012027The Role of the Cellular Transcription Factor, TAF7, in HIV Biology
Experimental Immunology BranchSinger, DinahZIA BC 012042Transgenerational Epigenetic Inheritance Mediated by a Core Promoter Element
Experimental Immunology BranchSinger, DinahZIA SC 010375TAF7: A Check-point Regulator in Transcription Initiation and Translation
Radiation Oncology BranchSmart, DeeDeeZIA BC 011222CNS sirtuins in radiation-induced vascular permeability and neurodegeneration
Radiation Oncology BranchSmart, DeeDeeZIA BC 011333Neuropsychological outcome measures in patients receiving whole brain radiation
Radiation Oncology BranchSmart, DeeDeeZIA BC 011790Metabolic imaging of the effects of brain radiotherapy
Laboratory of Genitourinary Cancer PathogenesisSowalsky, AdamZIA BC 011679Molecular alterations driving the development of primary prostate cancers
Laboratory of Genitourinary Cancer PathogenesisSowalsky, AdamZIA BC 011680Detection of prostate cancer using circulating tumor DNA
Laboratory of Genitourinary Cancer PathogenesisSowalsky, AdamZIA BC 011838Mechanisms of resistance to treatment in aggressive prostate cancers
Urologic Oncology BranchSrinivasan, RamaprasadZIA BC 011648Targeting Genetic and Metabolic Alterations in Distinct Subtypes of RCC
Urologic Oncology BranchSrinivasan, RamaprasadZIA BC 011920Novel Approaches to Targeting Cancers Associated with VHL Mutations
Mouse Cancer Genetics ProgramSt. Croix, BradZIA BC 010484Functional Analysis of TEM5 and TEM8
Mouse Cancer Genetics ProgramSt. Croix, BradZIA BC 010578Targeting TEMs in Preclinical Tumor Models
Mouse Cancer Genetics ProgramSt. Croix, BradZIA BC 010736Unraveling the function of CD276
Laboratory of Cellular OncologyStarrett, GabrielZIA BC 011894Biology of Virus-associated Cancers
Lymphoid Malignancies BranchStaudt, LouisZIA BC 011006Molecular diagnosis and outcome prediction in lymphoma
Lymphoid Malignancies BranchStaudt, LouisZIA BC 011007Functional genomic screens for molecular targets in cancer
Lymphoid Malignancies BranchStaudt, LouisZIA BC 011008Oncogenic mechanisms and molecular targets in lymphoma
Lymphoid Malignancies BranchStaudt, LouisZIA BC 011780Clinical development of mechanism-based lymphoma therapies
Women's Malignancies BranchSteeg, PatriciaZIA BC 010538Molecular Analysis of Breast Cancer Metastasis to the Brain
Women's Malignancies BranchSteeg, PatriciaZIA BC 011718Breast cancer aggressiveness in young patients
Women's Malignancies BranchSteeg, PatriciaZIA SC 000892Molecular Biology of the Metastatic Phenotype
OCD-OD AdminSteinberg, SethZID SC 007202Biostatistics and Data Management Section
Laboratory of Cell and Developmental SignalingSterneck, EstaZIA BC 010307Molecular Mechanisms Regulating Mouse Mammary Gland and Human Breast Tumor Cells
Laboratory of PathologyStetler-Stevenson, MaryaliceZIC BC 011093Flow Cytometric Detection of Malignant Cells in Body Fluids
Laboratory of PathologyStetler-Stevenson, MaryaliceZIC BC 011104Flow Cytometric Evaluation of Biomarkers
Laboratory of PathologyStetler-Stevenson, MaryaliceZIC SC 009372Flow Cytometric Analysis of Benign and Malignant Tumors
Laboratory of PathologyStetler-Stevenson, WilliamZIA BC 011204Development of TIMP-2 derivatives or strategies as biologic therapies for cancer
Laboratory of PathologyStetler-Stevenson, WilliamZIA SC 009179The Role of TIMPs in Cell Growth, Tumor Progression and Metastasis
Radiation Oncology BranchStracker, TravisZIA BC 012010Tousled like kinase signaling in cancer
Radiation Oncology BranchStracker, TravisZIA BC 012012Identification of radiosensitizers for prostate cancer
Laboratory of Tumor Immunology and BiologyStrauss, JuliusZIA BC 011547Cancer Immunotherapy Clinical Trials
Experimental Immunology BranchTakahama, YousukeZIA BC 011806Thymus biology
Laboratory of Genitourinary Cancer PathogenesisTakeda, DavidZIA BC 011965Mechanism of epigenetic activation during disease progression
Laboratory of Genitourinary Cancer PathogenesisTakeda, DavidZIA BC 011973Identification of epigenetic drivers of advanced prostate cancer
Laboratory of Cell BiologyTanner, KandiceZIA BC 011433The Role of Coherent Rotation in Adult Tissue Remodeling
Laboratory of Cell BiologyTanner, KandiceZIA BC 011524Mechanical regulation of the microenvironmental niche in skin tumorigenesis
Laboratory of Cell BiologyTanner, KandiceZIA BC 011559The role of the tumor biofilm in determining tissue tropism
Laboratory of Cell BiologyTanner, KandiceZIA BC 011903Synthetic bacteria as a targeted delivery system for small molecule therapeutics
Center for Structural BiologyTarasov, SergeyZIC BC 010965CCR Biophysics Resource Core
Laboratory of Cancer ImmunometabolismTarasova, NadyaZIA BC 011306Inhibitors of protein-protein interactions
Laboratory of Cancer ImmunometabolismTarasova, NadyaZIA BC 011307Self-assembling protoviral nanoparticles
Laboratory of Cancer ImmunometabolismTarasova, NadyaZIA BC 011944Development of COVID-19 cell entry inhibitors
Pediatric Oncology BranchTaylor, NaomiZIA BC 011923Metabolic regulation of T cell effector function and anti-tumor immunotherapy
Pediatric Oncology BranchTaylor, NaomiZIA BC 011924Reprogramming hematopoietic stem cell (HSC) differentiation via metabolic condit
Experimental Transplantation and Immunotherapy BranchTelford, WilliamZIC BC 011138ETIB FACS Core Facility
Experimental Transplantation and Immunotherapy BranchTelford, WilliamZIC BC 011139Application of novel laser technology for flow cytometric analysis
Neuro-Oncology BranchTerabe, MasakiZIA BC 011877Immunological Analysis of Brain Cancer
Mouse Cancer Genetics ProgramTessarollo, LinoZIA BC 010390Role of Neurotrophins in the Development of the Mammalian Nervous System
Mouse Cancer Genetics ProgramTessarollo, LinoZIA BC 010391Role of Trk Receptors in the Development and Function of Non-neuronal Structures
Mouse Cancer Genetics ProgramTessarollo, LinoZIC BC 011265Gene Targeting Facility
Pediatric Oncology BranchThiele, CarolZIA BC 010788Regulation of Differentiation of Pediatric Embryonal Tumors- Neuroblastoma
Pediatric Oncology BranchThiele, CarolZIA BC 010789Pathophysiologic Consequences of Neurotrophin Activation of Trk in Neuroblastoma
Pediatric Oncology BranchThiele, CarolZIA BC 012046Neuroblastoma Tumor Microenvironment: tumor growth and immune regulation
Developmental Therapeutics BranchThomas, AnishZIA BC 011793Exploiting DNA Replicative Stress for Novel Small Cell Lung Cancer Therapies
Radiation Oncology BranchTofilon, PhilipZIA BC 011372Microenvironmental regulation of glioblastoma radiosensitivity
Radiation Oncology BranchTofilon, PhilipZIA BC 011373Radiation-induced translational control of gene expression
Laboratory of Cellular OncologyTosato, GiovannaZIA BC 010782Study of the Roles of SDF1 and CXCR4 in Hematopoiesis
Laboratory of Cellular OncologyTosato, GiovannaZIA SC 010355Angiogenesis and Tumor Growth
Laboratory of Cellular OncologyTosato, GiovannaZIA SC 010356A Role for KSHV in the Pathogenesis of Malignancies
Laboratory of Integrative Cancer ImmunologyTrinchieri, GiorgioZIA BC 010793Role of inflammation, innate resistance, and immunity in carcinogenesis
Laboratory of Integrative Cancer ImmunologyTrinchieri, GiorgioZIA BC 011152Regulation of human dendritic cell activation
Laboratory of Integrative Cancer ImmunologyTrinchieri, GiorgioZIA BC 011153Role of microbiome in cancer and inflammation
Center for Structural BiologyTropea, JosephZIC BC 011016Protein Purification Core
Molecular Imaging BranchTurkbey, IsmailZIA BC 012062Imaging, image guided biopsy and treatment of prostate cancer
Molecular Imaging BranchTurkbey, IsmailZIH BC 012032CCR Artificial Intelligence Resource
RNA Biology LaboratoryValkov, EugeneZIA BC 011977Molecular Mechanisms of mRNA Regulation and Decay
Laboratory of Biochemistry and Molecular BiologyVidigal, JoanaZIA BC 011810Canonical and non-canonical roles of Argonaute proteins in mammals
Laboratory of Biochemistry and Molecular BiologyVidigal, JoanaZIA BC 011811CRISPR tools to dissect the coding and non-coding genome
Urologic Oncology BranchVocke, CathyZIC BC 011044Tissue Processing-Sequencing Facility
Laboratory of Cancer Biology and GeneticsWakefield, LalageZIA BC 005785TGF-betas in breast cancer progression
Laboratory of Cancer Biology and GeneticsWakefield, LalageZIA BC 010881Development of TGF-beta antagonists for cancer therapy
Lymphoid Malignancies BranchWaldmann, ThomasZIA BC 011946COVID-19 research efforts
Lymphoid Malignancies BranchWaldmann, ThomasZIA SC 004002IL-2:IL-15 : implications for cancer therapy
Lymphoid Malignancies BranchWaldmann, ThomasZIB BC 010906Interleukin-15 Production for Treatment of Patients with Metastatic Malignancy
Center for Structural BiologyWalters, KylieZIA BC 011490Ubiquitin signaling for protein degradation
Center for Structural BiologyWalters, KylieZIA BC 011627Mechanisms of function and targeting for complexes relevant to cancer biology
Laboratory of Cancer ImmunometabolismWang, Ji MingZIA BC 010015The Role of Cellular Receptors Involved in Inflammation and Tumor Progression
Laboratory of Cancer ImmunometabolismWang, Ji MingZIA BC 010725Role of Formylpeptide Receptors in Host Defense
Laboratory of Human CarcinogenesisWang, Xin WeiZIA BC 005793Mechanism of viral hepatitis-mediated hepatocarcinogenesis
Laboratory of Human CarcinogenesisWang, Xin WeiZIA BC 010313Molecular signatures for liver cancer diagnosis and treatment stratification
Laboratory of Human CarcinogenesisWang, Xin WeiZIA BC 010876The role of cancer stem cells in liver cancer heterogeneity and subtypes
Laboratory of Human CarcinogenesisWang, Xin WeiZIA BC 010877The identification of human hepatocellular carcinoma metastasis genes
Laboratory of Human CarcinogenesisWang, Xin WeiZIA BC 011951Viral exposure signatures may define individuals vulnerable for COVID-19
Laboratory of Human CarcinogenesisWang, Xin WeiZIC BC 012048Identification of viral exposure signatures for early detection of liver cancer
Center for Structural BiologyWang, Yun-XingZIA BC 010379Search for the Structural Basis of Biomacromolecular Function and Activity
Center for Structural BiologyWang, Yun-XingZIA BC 011669NCI X-ray free electron laser (XFEL) initiative
Center for Structural BiologyWang, Yun-XingZIC BC 011535SAXS Core
Center for Structural BiologyWaugh, DavidZIC BC 011868Protein Engineering Core
Laboratory of Cellular and Molecular BiologyWeigert, RobertoZIA BC 011682Molecular mechanisms of membrane remodeling
Laboratory of Cellular and Molecular BiologyWeigert, RobertoZIC BC 012030Intravital Microscopy Core
Laboratory of Protein Dynamics and SignalingWeissman, AllanZIA BC 009392Determining the Fate of Transmembrane Proteins
Laboratory of Protein Dynamics and SignalingWeissman, AllanZIA BC 010292Enzymes and Substrates of the Ubiquitin Conjugating System
Laboratory of Cell and Developmental SignalingWestlake, ChristopherZIA BC 011398Regulation of Ciliogenesis and Ciliary-related signaling
Laboratory of Molecular BiologyWickner, SueZIA BC 008710Molecular Chaperones and DNA Replication
Office of the DirectorWidemann, BrigitteZIA BC 011852MyPART: My Pediatric and Adult Rare Tumor Network - Cures
Pediatric Oncology BranchWidemann, BrigitteZIA SC 010354Therapies for patients with rare tumors and genetic tumor predisposition
Office of the DirectorWiener, LoriZIA BC 011874Graft-Versus-Host Disease Symptom Management-Cures
Lymphoid Malignancies BranchWilson, WyndhamZIA BC 010717Phase I study of bortezomib and DA-EPOCH-R with microarray in DLBCL
Lymphoid Malignancies BranchWilson, WyndhamZIA BC 010719Randomized Phase II study of borteozmib-EPOCH-R in Mantle cell lymphoma
Lymphoid Malignancies BranchWilson, WyndhamZIA BC 010728Phase III Study of R-CHOP v DA-EPOCH-R with microarray
Lymphoid Malignancies BranchWilson, WyndhamZIA BC 011354BCR Signaling in ABC DLBCL
Lymphoid Malignancies BranchWilson, WyndhamZIA BC 011654TEDDI-R in PCNSL
Lymphoid Malignancies BranchWilson, WyndhamZIA SC 006741Lymphoma Studies
Laboratory of Cancer ImmunometabolismWink, DavidZIA BC 010898Redox Mechanism Process of Angiogenesis and Wound Healing
Laboratory of Cancer ImmunometabolismWink, DavidZIA BC 010899Inflammation and cancer treatment
Laboratory of Cancer ImmunometabolismWink, DavidZIA BC 011190Chemical Biology of Nitroxyl (HNO)
Laboratory of Cancer ImmunometabolismWink, DavidZIA SC 007281Nitric Oxide as a Modifier of Oxidative Stress
Office of the DirectorWinkler-Pickett, RobinZIC BC 011596CCR Dedicated Cores
Basic Research LaboratoryWinkler, CherylZIA BC 010022Genetics of Complex Diseases and Health Disparities
Basic Research LaboratoryWinkler, CherylZIA BC 010297Identification of Genetic Factors Associated with Infectious Diseases
Experimental Immunology BranchWisniewski, JanZIC BC 010915EIB Microscopy Core Facility
Center for Structural BiologyWlodawer, AlexanderZIA BC 010348Protein Structure
Center for Structural BiologyWlodawer, AlexanderZIA BC 011966Chimeric ACE2 peptide ligand for diagnostic assays of SARS-CoV-2
Laboratory of Cancer ImmunometabolismWolf, MatthewZIA BC 012021Cancer Biomaterials Engineering
RNA Biology LaboratoryWolin, SandraZIA BC 011757Biogenesis, Function and Turnover of Noncoding RNAs
Office of the DirectorWood, BradfordZIA BC 011936Development of COVID-19 Imaging Tools with Artificial Intelligence
Office of the DirectorWood, BradfordZID BC 011242Center for Interventional Oncology
Experimental Immunology BranchWu, ChuanZIA BC 011755The role of Foxo1 for intestinal epithelial cells during mucosal immune response
Experimental Immunology BranchWu, ChuanZIA BC 011801CD101 controls intraepithelial cells (IELs) for intestinal barrier integrity
Experimental Immunology BranchWu, ChuanZIA BC 012034IL-33 promotes serotonin release from enterochromaffin cells
RNA Biology LaboratoryWu, Colin (Chih-Chien)ZIA BC 012037Noncanonical functions of the ribosome in response to cellular stress
Neuro-Oncology BranchWu, JingZIA BC 011840Discovering novel therapies for glioma patients
Neuro-Oncology BranchWu, JingZIA BC 011841Understanding IDH mutant gliomas
Laboratory of PathologyXi, LiqiangZIC BC 011079Molecular Diagnostics Core Laboratory
Laboratory of PathologyXi, LiqiangZID BC 011792Development of FISH Molecular Diagnostics to support Clinical Trials at NCI
Laboratory of PathologyXi, LiqiangZID BC 011929Methylation Array Profiling as a New Clinical Diagnostic Test
Laboratory of PathologyXi, LiqiangZID BC 011959NCI COMPASS
Laboratory of Cell BiologyXia, DiZIA BC 010319Structural Basis of Biological Membrane Protein Functions and Drug Resistance
Laboratory of Cell BiologyXia, DiZIA BC 010600AAA Proteins, Their Functions and Related Diseases
Laboratory of Cell BiologyXia, DiZIA BC 011972Mechanism of Inhibition of Entry Inhibitors against SARS-CoVs
Thoracic and GI Malignancies BranchXie, ChangqingZIA BC 011888Cancer Stem Cells in Cholangiocarcinoma
Cancer and Developmental Biology LaboratoryYamaguchi, TerryZIA BC 010345The Role of Wnt Genes in Vertebrate Development and Cancer
Neuro-Oncology BranchYang, Chun ZhangZIA BC 011684Chemo-sensitizing IDH1-mutated glioma by molecular targeting
Neuro-Oncology BranchYang, Chun ZhangZIA BC 011761Nrf2-goverened metabolic reprogram in IDH1-mutated glioma
Neuro-Oncology BranchYang, Chun ZhangZIA BC 011876Establish Preclinical Model for IDH-mutated Glioma
Surgery BranchYang, JamesZIA BC 011337Generation of T-cell receptors recognizing antigens on non-melanoma tumors
Surgery BranchYang, JamesZIA BC 011651Laboratory and Clinical studies on T-cells recognizing NSCLC
Surgery BranchYang, JamesZIA BC 011843Identification and use of T-cell receptors recognizing common tumor mutations
Laboratory of Cancer Biology and GeneticsYang, LiZIA BC 011163Myeloid TGFbeta signaling in breast cancer metastasis
Laboratory of Cancer Biology and GeneticsYang, LiZIA BC 011165Role of inflammation in epigenetic alterations of metastatic cancer cells
HIV and AIDS Malignancy BranchYarchoan, RobertZIA BC 010885Study of Tumor Pathogenesis and Development of Therapies for AIDS Malignancies
HIV and AIDS Malignancy BranchYarchoan, RobertZIA BC 010888Clinical Trials of Patients with AIDS-Related Malignancies
HIV and AIDS Malignancy BranchYarchoan, RobertZIA BC 011945Study of and development of antiviral drugs against SARS-CoV2 protease
HIV and AIDS Malignancy BranchYarchoan, RobertZIA SC 006737Development of Preventive Strategies and Therapy for HIV Infection
Laboratory of Cell and Developmental SignalingYohe, MarielleZIA BC 011804Dual Blockade of IGF1R and MEK synergistically inhibits pediatric cancers
Laboratory of Cell and Developmental SignalingYohe, MarielleZIA BC 011805Defining the Mechanism of Action of Rigosertib in Pediatric Cancers
Laboratory of Cell and Developmental SignalingYohe, MarielleZIA BC 011869Advancing RAS and RASopathy Therapies
Laboratory of Cell and Developmental SignalingYohe, MarielleZIA BC 011892Targeting RAS in Pediatric Cancer
Laboratory of Cell and Developmental SignalingYohe, MarielleZIA BC 011993Regulation of differentiation and invasion in RMS by ASAP1
Chemical Biology LaboratoryYoo, EunaZIA BC 011961Synthesis and characterization of covalent ligand library
Chemical Biology LaboratoryYoo, EunaZIA BC 011962Understanding functional roles and regulation of granzyme
Chemical Biology LaboratoryYoo, EunaZIA BC 011963Targeting ISG15 and USP18
Cancer Data Science LaboratoryYoukharibache, PhilippeZIA BC 011990Structural basis of viral RBDs binding to cell receptors
Cancer Data Science LaboratoryYoukharibache, PhilippeZIA BC 011997CAR and Antibodies Structure-Activity Relationships and molecular architecture
Cancer Data Science LaboratoryYoukharibache, PhilippeZIH BC 012005Structural data science methods and software to study immunotherapeutic proteins
Laboratory of Cancer ImmunometabolismYoung, HowardZIA BC 009283Consequences of chronic Interferon-gamma expression on the host
Lymphoid Malignancies BranchYoung, RyanZIA BC 011999Identifying novel modes of oncogenic signaling in multiple myeloma
Laboratory of Cancer Biology and GeneticsYuspa, StuartZIA BC 004504Interacting Signaling Pathways that Initiate Squamous Cell Carcinogenesis
Laboratory of Cancer Biology and GeneticsYuspa, StuartZIA BC 005445Pathways that Suppress or Accelerate Premalignant Progression of Squamous Cancer
Surgical Oncology ProgramZeiger, MarthaZIE BC 011992Training and Development of Outstanding Surgeon Scientists
Center for Structural BiologyZhang, PingZIA BC 011744Mechanistic Analyses of kinase signaling complexes
Laboratory of Cellular and Molecular BiologyZhang, YingZIA BC 010419Molecular Mechanisms of TGF-beta Signaling Pathway
Laboratory of Cellular and Molecular BiologyZhang, YingZIA BC 011168Physiological and pathological functions of E3 ubiquitin ligases Smurfs
Thoracic and GI Malignancies BranchZhao, ChenZIA BC 012008Study interactions between lung microbiota and immune cells in NSCLC
Thoracic and GI Malignancies BranchZhao, ChenZIA BC 012011Investigate heterogeneous neutrophils in NSCLC
HIV DRP Retroviral Replication LaboratoryZheng, Zhi-MingZIA SC 010357Gene Expression and Post-Transcriptional Regulation of DNA Tumor Viruses
Neuro-Oncology BranchZhuang, ZhengpingZIA BC 011773Hypoxia signaling in cancer development
Laboratory of Cell BiologyZhurkin, VictorZIA BC 010844DNA Folding in Chromatin at the Supra-nucleosome Level
Laboratory of Cell BiologyZhurkin, VictorZIA BC 010845p53-induced Regulation of Transcription in the Chromatin Context
HIV and AIDS Malignancy BranchZiegelbauer, JosephZIA BC 011176Functions of KSHV microRNAs and circular RNAs
HIV and AIDS Malignancy BranchZiegelbauer, JosephZIA BC 012047Virus host interactions in clinical samples
Last updated by Boersma, Brenda (NIH/NCI) [E] on Nov 09, 2021